| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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287 genes differentially expressed following the BRD-K43389698_BMS-387032_LNCAP_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| A2M | alpha-2-macroglobulin |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADD3 | adducin 3 (gamma) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANKRD36B | ankyrin repeat domain 36B |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOE | apolipoprotein E |
| AQP1 | aquaporin 1 (Colton blood group) |
| AQP3 | aquaporin 3 (Gill blood group) |
| AQP9 | aquaporin 9 |
| ATG12 | autophagy related 12 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BSG | basigin (Ok blood group) |
| C5AR1 | complement component 5a receptor 1 |
| CA2 | carbonic anhydrase II |
| CAV2 | caveolin 2 |
| CD47 | CD47 molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CETN2 | centrin, EF-hand protein, 2 |
| CLU | clusterin |
| COCH | cochlin |
| COL18A1 | collagen, type XVIII, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL5A2 | collagen, type V, alpha 2 |
| COL6A3 | collagen, type VI, alpha 3 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CTTN | cortactin |
| CYBRD1 | cytochrome b reductase 1 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) |
| DPYSL3 | dihydropyrimidinase-like 3 |
| EGR1 | early growth response 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| EPCAM | epithelial cell adhesion molecule |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOLR1 | folate receptor 1 (adult) |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FST | follistatin |
| G0S2 | G0/G1 switch 2 |
| GDI1 | GDP dissociation inhibitor 1 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 |
| GPM6A | glycoprotein M6A |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX3 | glutathione peroxidase 3 |
| GRB14 | growth factor receptor-bound protein 14 |
| GSTP1 | glutathione S-transferase pi 1 |
| GUK1 | guanylate kinase 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1C | histone cluster 1, H1c |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HLA-E | major histocompatibility complex, class I, E |
| HLA-G | major histocompatibility complex, class I, G |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HP | haptoglobin |
| HRSP12 | heat-responsive protein 12 |
| IDS | iduronate 2-sulfatase |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LRRC17 | leucine rich repeat containing 17 |
| LTA4H | leukotriene A4 hydrolase |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MEIS2 | Meis homeobox 2 |
| METRN | meteorin, glial cell differentiation regulator |
| MSLN | mesothelin |
| MSRB1 | methionine sulfoxide reductase B1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NTS | neurotensin |
| NUCB1 | nucleobindin 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PFKM | phosphofructokinase, muscle |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLTP | phospholipid transfer protein |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PSPH | phosphoserine phosphatase |
| RBP1 | retinol binding protein 1, cellular |
| RGCC | regulator of cell cycle |
| RGS1 | regulator of G-protein signaling 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SNX10 | sorting nexin 10 |
| SORT1 | sortilin 1 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| STC1 | stanniocalcin 1 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 |
| TPP1 | tripeptidyl peptidase I |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSTA3 | tissue specific transplantation antigen P35B |
| TTC3 | tetratricopeptide repeat domain 3 |
| TUBA1A | tubulin, alpha 1a |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VAMP7 | vesicle-associated membrane protein 7 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ADRB2 | adrenoceptor beta 2, surface |
| AHNAK | AHNAK nucleoprotein |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AMD1 | adenosylmethionine decarboxylase 1 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| ARF6 | ADP-ribosylation factor 6 |
| ASS1 | argininosuccinate synthase 1 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 |
| AUTS2 | autism susceptibility candidate 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BAG5 | BCL2-associated athanogene 5 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CA12 | carbonic anhydrase XII |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CANT1 | calcium activated nucleotidase 1 |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CHMP7 | charged multivesicular body protein 7 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 |
| CSNK1D | casein kinase 1, delta |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DEPDC1 | DEP domain containing 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP7 | dual specificity phosphatase 7 |
| EFNA4 | ephrin-A4 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FASTKD5 | FAST kinase domains 5 |
| FBL | fibrillarin |
| FCGBP | Fc fragment of IgG binding protein |
| FOXO3 | forkhead box O3 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAS1 | growth arrest-specific 1 |
| GATA2 | GATA binding protein 2 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| GPATCH8 | G patch domain containing 8 |
| GRB10 | growth factor receptor-bound protein 10 |
| GSPT2 | G1 to S phase transition 2 |
| H2AFX | H2A histone family, member X |
| HMGB2 | high mobility group box 2 |
| HOXC6 | homeobox C6 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| INHBB | inhibin, beta B |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIF20A | kinesin family member 20A |
| KRT23 | keratin 23, type I |
| KRT7 | keratin 7, type II |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMNB1 | lamin B1 |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAPK6 | mitogen-activated protein kinase 6 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MB | myoglobin |
| MED1 | mediator complex subunit 1 |
| METTL3 | methyltransferase like 3 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MYBPC1 | myosin binding protein C, slow type |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NEK2 | NIMA-related kinase 2 |
| NET1 | neuroepithelial cell transforming 1 |
| NFIB | nuclear factor I/B |
| NGDN | neuroguidin, EIF4E binding protein |
| NKX3-1 | NK3 homeobox 1 |
| NOL11 | nucleolar protein 11 |
| NOP56 | NOP56 ribonucleoprotein |
| NUP62 | nucleoporin 62kDa |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PCGF2 | polycomb group ring finger 2 |
| PCNA | proliferating cell nuclear antigen |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLAC8 | placenta-specific 8 |
| PLCB4 | phospholipase C, beta 4 |
| PLK1 | polo-like kinase 1 |
| POSTN | periostin, osteoblast specific factor |
| PRPF4 | pre-mRNA processing factor 4 |
| PRPF4B | pre-mRNA processing factor 4B |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RAB14 | RAB14, member RAS oncogene family |
| RIN2 | Ras and Rab interactor 2 |
| RNF139 | ring finger protein 139 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| RPL39L | ribosomal protein L39-like |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SASH1 | SAM and SH3 domain containing 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SMAD1 | SMAD family member 1 |
| STMN2 | stathmin 2 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
| TBX3 | T-box 3 |
| TFAM | transcription factor A, mitochondrial |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM97 | transmembrane protein 97 |
| TMX4 | thioredoxin-related transmembrane protein 4 |
| TOB1 | transducer of ERBB2, 1 |
| TOB2 | transducer of ERBB2, 2 |
| TOMM70A | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) |
| TOX3 | TOX high mobility group box family member 3 |
| TSPYL4 | TSPY-like 4 |
| TSPYL5 | TSPY-like 5 |
| TXLNA | taxilin alpha |
| UCK2 | uridine-cytidine kinase 2 |
| USP22 | ubiquitin specific peptidase 22 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| VGLL4 | vestigial-like family member 4 |
| WDR82 | WD repeat domain 82 |
| XBP1 | X-box binding protein 1 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF217 | zinc finger protein 217 |
