| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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191 genes differentially expressed following the BRD-K44100512_KIN001-043_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ADIRF | adipogenesis regulatory factor |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| BMP4 | bone morphogenetic protein 4 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CARS | cysteinyl-tRNA synthetase |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFB | complement factor B |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLU | clusterin |
| CTH | cystathionine gamma-lyase |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DACH1 | dachshund family transcription factor 1 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| EFNB2 | ephrin-B2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| EPRS | glutamyl-prolyl-tRNA synthetase |
| EREG | epiregulin |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
| FAT1 | FAT atypical cadherin 1 |
| FHL2 | four and a half LIM domains 2 |
| FOLR1 | folate receptor 1 (adult) |
| GARS | glycyl-tRNA synthetase |
| GDF15 | growth differentiation factor 15 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPX2 | glutathione peroxidase 2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HMOX1 | heme oxygenase 1 |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFRD1 | interferon-related developmental regulator 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KAZN | kazrin, periplakin interacting protein |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LRRN3 | leucine rich repeat neuronal 3 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAB21L2 | mab-21-like 2 (C. elegans) |
| MX1 | MX dynamin-like GTPase 1 |
| NAV2 | neuron navigator 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUCB2 | nucleobindin 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RBP1 | retinol binding protein 1, cellular |
| RGS1 | regulator of G-protein signaling 1 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SOX4 | SRY (sex determining region Y)-box 4 |
| STMN2 | stathmin 2 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TPM4 | tropomyosin 4 |
| TRAM1 | translocation associated membrane protein 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D1 | TSC22 domain family, member 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| XBP1 | X-box binding protein 1 |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| APOD | apolipoprotein D |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ASPN | asporin |
| BCHE | butyrylcholinesterase |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CAV2 | caveolin 2 |
| CCNA2 | cyclin A2 |
| CD200 | CD200 molecule |
| CDK1 | cyclin-dependent kinase 1 |
| CDK14 | cyclin-dependent kinase 14 |
| CENPU | centromere protein U |
| CLDN10 | claudin 10 |
| COL15A1 | collagen, type XV, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| COL5A2 | collagen, type V, alpha 2 |
| COL6A2 | collagen, type VI, alpha 2 |
| DCN | decorin |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DST | dystonin |
| EAPP | E2F-associated phosphoprotein |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| F2R | coagulation factor II (thrombin) receptor |
| FABP7 | fatty acid binding protein 7, brain |
| FGF13 | fibroblast growth factor 13 |
| FN1 | fibronectin 1 |
| FSTL1 | follistatin-like 1 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GPM6B | glycoprotein M6B |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| H2AFV | H2A histone family, member V |
| H2AFX | H2A histone family, member X |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H4C | histone cluster 1, H4c |
| HMGB1 | high mobility group box 1 |
| HMGB2 | high mobility group box 2 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGF1R | insulin-like growth factor 1 receptor |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGL | immunoglobulin lambda locus |
| INPP5F | inositol polyphosphate-5-phosphatase F |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| ITM2A | integral membrane protein 2A |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KIF20A | kinesin family member 20A |
| KRT5 | keratin 5, type II |
| LAMA4 | laminin, alpha 4 |
| LHFP | lipoma HMGIC fusion partner |
| LMNB1 | lamin B1 |
| MAGEA3 | melanoma antigen family A3 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MCM5 | minichromosome maintenance complex component 5 |
| MEF2C | myocyte enhancer factor 2C |
| MOK | MOK protein kinase |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1X | metallothionein 1X |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 |
| NID1 | nidogen 1 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PLAT | plasminogen activator, tissue |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PODXL | podocalyxin-like |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POSTN | periostin, osteoblast specific factor |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRSS23 | protease, serine, 23 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
| RDX | radixin |
| RRM2 | ribonucleotide reductase M2 |
| S100A7 | S100 calcium binding protein A7 |
| SFN | stratifin |
| SFRP1 | secreted frizzled-related protein 1 |
| SNX10 | sorting nexin 10 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPARCL1 | SPARC-like 1 (hevin) |
| SRPX | sushi-repeat containing protein, X-linked |
| STMN1 | stathmin 1 |
| TCF4 | transcription factor 4 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| THBS2 | thrombospondin 2 |
| THY1 | Thy-1 cell surface antigen |
| TMSB15A | thymosin beta 15a |
| TNS3 | tensin 3 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPM1 | tropomyosin 1 (alpha) |
| TUBA1A | tubulin, alpha 1a |
| TXNIP | thioredoxin interacting protein |
| VCAN | versican |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 |
| ZBTB16 | zinc finger and BTB domain containing 16 |
