Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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120 genes differentially expressed following the BRD-K44100512_KIN001-043_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AK4 | adenylate kinase 4 |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AREG | amphiregulin |
BAG2 | BCL2-associated athanogene 2 |
BST2 | bone marrow stromal cell antigen 2 |
CCL20 | chemokine (C-C motif) ligand 20 |
CD69 | CD69 molecule |
CDA | cytidine deaminase |
COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DKC1 | dyskeratosis congenita 1, dyskerin |
DUSP5 | dual specificity phosphatase 5 |
DUSP6 | dual specificity phosphatase 6 |
ELOVL6 | ELOVL fatty acid elongase 6 |
ESR1 | estrogen receptor 1 |
FABP4 | fatty acid binding protein 4, adipocyte |
FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
FOSL1 | FOS-like antigen 1 |
G0S2 | G0/G1 switch 2 |
GPX2 | glutathione peroxidase 2 |
HBEGF | heparin-binding EGF-like growth factor |
HOMER1 | homer scaffolding protein 1 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IER3 | immediate early response 3 |
ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LIF | leukemia inhibitory factor |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MMP12 | matrix metallopeptidase 12 |
PAEP | progestagen-associated endometrial protein |
PDGFC | platelet derived growth factor C |
PGK1 | phosphoglycerate kinase 1 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PLEK2 | pleckstrin 2 |
PPARG | peroxisome proliferator-activated receptor gamma |
PPIF | peptidylprolyl isomerase F |
PRKCH | protein kinase C, eta |
RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SORD | sorbitol dehydrogenase |
SPP1 | secreted phosphoprotein 1 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
THBD | thrombomodulin |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TMX2 | thioredoxin-related transmembrane protein 2 |
TPST2 | tyrosylprotein sulfotransferase 2 |
TREM1 | triggering receptor expressed on myeloid cells 1 |
TSPAN7 | tetraspanin 7 |
VEGFA | vascular endothelial growth factor A |
ZNF91 | zinc finger protein 91 |
Symbol | Name |
---|---|
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
ARMCX1 | armadillo repeat containing, X-linked 1 |
BEX1 | brain expressed, X-linked 1 |
BLNK | B-cell linker |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CDK19 | cyclin-dependent kinase 19 |
CHGB | chromogranin B |
COL1A2 | collagen, type I, alpha 2 |
CRABP1 | cellular retinoic acid binding protein 1 |
CTBP2 | C-terminal binding protein 2 |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
DLK1 | delta-like 1 homolog (Drosophila) |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
FSTL1 | follistatin-like 1 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GRB7 | growth factor receptor-bound protein 7 |
GSTA1 | glutathione S-transferase alpha 1 |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
HIST1H2BK | histone cluster 1, H2bk |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMGN3 | high mobility group nucleosomal binding domain 3 |
HSPA2 | heat shock 70kDa protein 2 |
IFITM3 | interferon induced transmembrane protein 3 |
IFT57 | intraflagellar transport 57 |
IGFBP7 | insulin-like growth factor binding protein 7 |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
KLHDC2 | kelch domain containing 2 |
KRT14 | keratin 14, type I |
KRT5 | keratin 5, type II |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
NFIB | nuclear factor I/B |
PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
PDGFD | platelet derived growth factor D |
PEG10 | paternally expressed 10 |
PNMAL1 | paraneoplastic Ma antigen family-like 1 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PSIP1 | PC4 and SFRS1 interacting protein 1 |
RGS5 | regulator of G-protein signaling 5 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
SGCE | sarcoglycan, epsilon |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
SNAP25 | synaptosomal-associated protein, 25kDa |
SOX11 | SRY (sex determining region Y)-box 11 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TFPI2 | tissue factor pathway inhibitor 2 |
TMSB15B | thymosin beta 15B |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPM2 | tropomyosin 2 (beta) |
TPPP3 | tubulin polymerization-promoting protein family member 3 |
TSC22D3 | TSC22 domain family, member 3 |
TUBA1A | tubulin, alpha 1a |
TWIST1 | twist family bHLH transcription factor 1 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
VIM | vimentin |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
XIST | X inactive specific transcript (non-protein coding) |
ZFP36L2 | ZFP36 ring finger protein-like 2 |