| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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107 genes differentially expressed following the BRD-K44100512_KIN001-043_LNCAP_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| BST2 | bone marrow stromal cell antigen 2 |
| CCND2 | cyclin D2 |
| CD163 | CD163 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CFH | complement factor H |
| CTSS | cathepsin S |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYTL1 | cytokine-like 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FNDC3B | fibronectin type III domain containing 3B |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GDF15 | growth differentiation factor 15 |
| GSTP1 | glutathione S-transferase pi 1 |
| HMOX1 | heme oxygenase 1 |
| ICAM2 | intercellular adhesion molecule 2 |
| IER5 | immediate early response 5 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| ITM2A | integral membrane protein 2A |
| LCN2 | lipocalin 2 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFAP5 | microfibrillar associated protein 5 |
| MMP12 | matrix metallopeptidase 12 |
| NPY1R | neuropeptide Y receptor Y1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OLFM1 | olfactomedin 1 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PYCARD | PYD and CARD domain containing |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RTN3 | reticulon 3 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SPP1 | secreted phosphoprotein 1 |
| TARS | threonyl-tRNA synthetase |
| TF | transferrin |
| TRIB3 | tribbles pseudokinase 3 |
| WBP5 | WW domain binding protein 5 |
| WSB1 | WD repeat and SOCS box containing 1 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADCK3 | aarF domain containing kinase 3 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ANPEP | alanyl (membrane) aminopeptidase |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BMP2 | bone morphogenetic protein 2 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CA2 | carbonic anhydrase II |
| CD9 | CD9 molecule |
| COL13A1 | collagen, type XIII, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EMP2 | epithelial membrane protein 2 |
| ETV1 | ets variant 1 |
| GPM6B | glycoprotein M6B |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGF1R | insulin-like growth factor 1 receptor |
| ITGA6 | integrin, alpha 6 |
| KLK2 | kallikrein-related peptidase 2 |
| KLK3 | kallikrein-related peptidase 3 |
| KRT15 | keratin 15, type I |
| KRT8 | keratin 8, type II |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MLPH | melanophilin |
| MX2 | MX dynamin-like GTPase 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NKX3-1 | NK3 homeobox 1 |
| NNMT | nicotinamide N-methyltransferase |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUP93 | nucleoporin 93kDa |
| RGS13 | regulator of G-protein signaling 13 |
| RGS2 | regulator of G-protein signaling 2 |
| SDC2 | syndecan 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TCF4 | transcription factor 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TMX4 | thioredoxin-related transmembrane protein 4 |
| TNC | tenascin C |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TUBA1A | tubulin, alpha 1a |
| TXNIP | thioredoxin interacting protein |
| VAMP8 | vesicle-associated membrane protein 8 |
| VNN1 | vanin 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
