BRD-K44136596_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K44136596_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMIGO2 adhesion molecule with Ig-like domain 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL8A2 collagen, type VIII, alpha 2
COL9A2 collagen, type IX, alpha 2
HAPLN1 hyaluronan and proteoglycan link protein 1
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGL immunoglobulin lambda locus
MMP9 matrix metallopeptidase 9
PAWR PRKC, apoptosis, WT1, regulator
RGS2 regulator of G-protein signaling 2
S100A7 S100 calcium binding protein A7
SLC35F2 solute carrier family 35, member F2
SULF1 sulfatase 1
TM4SF4 transmembrane 4 L six family member 4
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
AHR aryl hydrocarbon receptor
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
EGFR epidermal growth factor receptor
F13A1 coagulation factor XIII, A1 polypeptide
IER3 immediate early response 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MGLL monoglyceride lipase
PPARG peroxisome proliferator-activated receptor gamma
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
TIMP3 TIMP metallopeptidase inhibitor 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2