BRD-K44227013_ponatinib_A549_24_h_3.33_um Gene Set
Genes
36 genes differentially expressed following the BRD-K44227013_ponatinib_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
|
ASNS
|
asparagine synthetase (glutamine-hydrolyzing)
|
|
ATF4
|
activating transcription factor 4
|
|
BHLHE41
|
basic helix-loop-helix family, member e41
|
|
CBS
|
cystathionine-beta-synthase
|
|
CRYAB
|
crystallin, alpha B
|
|
ELOVL6
|
ELOVL fatty acid elongase 6
|
|
FADS1
|
fatty acid desaturase 1
|
|
FDPS
|
farnesyl diphosphate synthase
|
|
GARS
|
glycyl-tRNA synthetase
|
|
HTRA1
|
HtrA serine peptidase 1
|
|
INSIG1
|
insulin induced gene 1
|
|
LDLR
|
low density lipoprotein receptor
|
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
|
NUPR1
|
nuclear protein, transcriptional regulator, 1
|
|
OSBPL1A
|
oxysterol binding protein-like 1A
|
|
PAPSS2
|
3'-phosphoadenosine 5'-phosphosulfate synthase 2
|
|
PHGDH
|
phosphoglycerate dehydrogenase
|
|
PLCB4
|
phospholipase C, beta 4
|
|
PSAT1
|
phosphoserine aminotransferase 1
|
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
|
SLC38A1
|
solute carrier family 38, member 1
|
|
SLC7A11
|
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
|
|
SYT1
|
synaptotagmin I
|
|
TSC22D3
|
TSC22 domain family, member 3
|
decreased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
AKAP12
|
A kinase (PRKA) anchor protein 12
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
|
CRIP1
|
cysteine-rich protein 1 (intestinal)
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
FOSL1
|
FOS-like antigen 1
|
|
IER3
|
immediate early response 3
|
|
KRT15
|
keratin 15, type I
|
|
MYCBP
|
MYC binding protein
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
|
TNC
|
tenascin C
|
