| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
91 genes differentially expressed following the BRD-K44227013_ponatinib_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACLY | ATP citrate lyase |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| C1QB | complement component 1, q subcomponent, B chain |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CALD1 | caldesmon 1 |
| CANX | calnexin |
| CAV2 | caveolin 2 |
| CLIC4 | chloride intracellular channel 4 |
| COL1A1 | collagen, type I, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| COL5A2 | collagen, type V, alpha 2 |
| COPA | coatomer protein complex, subunit alpha |
| CPD | carboxypeptidase D |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CXADR | coxsackie virus and adenovirus receptor |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DCAF7 | DDB1 and CUL4 associated factor 7 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPCAM | epithelial cell adhesion molecule |
| EPHA3 | EPH receptor A3 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GPX3 | glutathione peroxidase 3 |
| HIPK1 | homeodomain interacting protein kinase 1 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| JUP | junction plakoglobin |
| LBH | limb bud and heart development |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MSMB | microseminoprotein, beta- |
| PERP | PERP, TP53 apoptosis effector |
| PHGDH | phosphoglycerate dehydrogenase |
| PKN2 | protein kinase N2 |
| PLEC | plectin |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) |
| PRKCI | protein kinase C, iota |
| PSPH | phosphoserine phosphatase |
| RAP2A | RAP2A, member of RAS oncogene family |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERINC3 | serine incorporator 3 |
| SF1 | splicing factor 1 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TNS3 | tensin 3 |
| TPR | translocated promoter region, nuclear basket protein |
| TRAK2 | trafficking protein, kinesin binding 2 |
| TWF1 | twinfilin actin binding protein 1 |
| WAC | WW domain containing adaptor with coiled-coil |
| YME1L1 | YME1-like 1 ATPase |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| Symbol | Name |
|---|---|
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ASRGL1 | asparaginase like 1 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CD200 | CD200 molecule |
| CD47 | CD47 molecule |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| GAS7 | growth arrest-specific 7 |
| HOXC6 | homeobox C6 |
| IFI27 | interferon, alpha-inducible protein 27 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MMP12 | matrix metallopeptidase 12 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MSX1 | msh homeobox 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTGES | prostaglandin E synthase |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPIA | ribose 5-phosphate isomerase A |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| TBX3 | T-box 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM176B | transmembrane protein 176B |
| TRIM2 | tripartite motif containing 2 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
