BRD-K44540157_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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44 genes differentially expressed following the BRD-K44540157_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CSRP1 cysteine and glycine-rich protein 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
FASN fatty acid synthase
HAL histidine ammonia-lyase
HSPA1A heat shock 70kDa protein 1A
KIAA0355 KIAA0355
KRT23 keratin 23, type I
MAPT microtubule-associated protein tau
MMP7 matrix metallopeptidase 7
PEBP1 phosphatidylethanolamine binding protein 1
PODXL podocalyxin-like
SEPT9 septin 9
TACC2 transforming, acidic coiled-coil containing protein 2
TCF4 transcription factor 4
TSPAN8 tetraspanin 8
ZYX zyxin

decreased expression

Symbol Name
BTG3 BTG family, member 3
C1R complement component 1, r subcomponent
CASP1 caspase 1, apoptosis-related cysteine peptidase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSTA cystatin A (stefin A)
CXCL14 chemokine (C-X-C motif) ligand 14
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GPX1 glutathione peroxidase 1
GUCY1B3 guanylate cyclase 1, soluble, beta 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1R1 interleukin 1 receptor, type I
KDM5D lysine (K)-specific demethylase 5D
LY6E lymphocyte antigen 6 complex, locus E
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MDFIC MyoD family inhibitor domain containing
NPTX2 neuronal pentraxin II
PLAGL1 pleiomorphic adenoma gene-like 1
REG3A regenerating islet-derived 3 alpha
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SAT1 spermidine/spermine N1-acetyltransferase 1
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
TGFBI transforming growth factor, beta-induced, 68kDa
WBP5 WW domain binding protein 5