BRD-K44849676_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K44849676_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANK2 ankyrin 2, neuronal
ARID5B AT rich interactive domain 5B (MRF1-like)
BHLHE41 basic helix-loop-helix family, member e41
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
COL6A2 collagen, type VI, alpha 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EIF1 eukaryotic translation initiation factor 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOXC10 homeobox C10
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KLF11 Kruppel-like factor 11
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MME membrane metallo-endopeptidase
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NT5E 5'-nucleotidase, ecto (CD73)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
RNF167 ring finger protein 167
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SQSTM1 sequestosome 1
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TSPYL5 TSPY-like 5
TXNRD1 thioredoxin reductase 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
C7 complement component 7
CALD1 caldesmon 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
IQGAP2 IQ motif containing GTPase activating protein 2
LITAF lipopolysaccharide-induced TNF factor
PLK1 polo-like kinase 1
PTCH1 patched 1
SLPI secretory leukocyte peptidase inhibitor
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
TSPAN13 tetraspanin 13
VAT1 vesicle amine transport 1
Funding