BRD-K45031696_N-(4-(5-(benzo[d][1,3]dioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl)phenyl)-2-(phenylthio)acetamide Secin H3_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K45031696_N-(4-(5-(benzo[d][1,3]dioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl)phenyl)-2-(phenylthio)acetamide Secin H3_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AGR2 anterior gradient 2
ANXA1 annexin A1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C1QB complement component 1, q subcomponent, B chain
CBR3 carbonyl reductase 3
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD163 CD163 molecule
CD47 CD47 molecule
CDC20 cell division cycle 20
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHN2 chimerin 2
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
COLEC12 collectin sub-family member 12
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
F13A1 coagulation factor XIII, A1 polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
GALC galactosylceramidase
HOPX HOP homeobox
ICAM2 intercellular adhesion molecule 2
IL1RN interleukin 1 receptor antagonist
ITM2A integral membrane protein 2A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM5D lysine (K)-specific demethylase 5D
KRT15 keratin 15, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMO4 LIM domain only 4
LTBP1 latent transforming growth factor beta binding protein 1
LUM lumican
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGP matrix Gla protein
MMP12 matrix metallopeptidase 12
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
NID2 nidogen 2 (osteonidogen)
NRN1 neuritin 1
NUPR1 nuclear protein, transcriptional regulator, 1
PDLIM4 PDZ and LIM domain 4
PTN pleiotrophin
QKI QKI, KH domain containing, RNA binding
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RELN reelin
RGS1 regulator of G-protein signaling 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SPARCL1 SPARC-like 1 (hevin)
SRGN serglycin
SRPX sushi-repeat containing protein, X-linked
TIAM1 T-cell lymphoma invasion and metastasis 1
TYROBP TYRO protein tyrosine kinase binding protein
VSIG4 V-set and immunoglobulin domain containing 4
VWA5A von Willebrand factor A domain containing 5A
WDR7 WD repeat domain 7
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CCL5 chemokine (C-C motif) ligand 5
CD24 CD24 molecule
CST7 cystatin F (leukocystatin)
ENO1 enolase 1, (alpha)
F11R F11 receptor
HBB hemoglobin, beta
IGHM immunoglobulin heavy constant mu
IL32 interleukin 32
LAPTM4B lysosomal protein transmembrane 4 beta
LOC100505650 uncharacterized LOC100505650
NR2F6 nuclear receptor subfamily 2, group F, member 6
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPON1 spondin 1, extracellular matrix protein
TGFBR3 transforming growth factor, beta receptor III
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
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