BRD-K45842176_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K45842176_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ACSL1 acyl-CoA synthetase long-chain family member 1
AKR1C3 aldo-keto reductase family 1, member C3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CHN2 chimerin 2
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
DEPTOR DEP domain containing MTOR-interacting protein
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
FKBP5 FK506 binding protein 5
FNDC3B fibronectin type III domain containing 3B
FRY furry homolog (Drosophila)
GADD45B growth arrest and DNA-damage-inducible, beta
GAS1 growth arrest-specific 1
GMDS GDP-mannose 4,6-dehydratase
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
KLF9 Kruppel-like factor 9
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEBL nebulette
NFIL3 nuclear factor, interleukin 3 regulated
NNMT nicotinamide N-methyltransferase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
RAB20 RAB20, member RAS oncogene family
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TF transferrin
TFF3 trefoil factor 3 (intestinal)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNC tenascin C
TSC22D3 TSC22 domain family, member 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
XBP1 X-box binding protein 1

decreased expression

Symbol Name
CAST calpastatin
CCL5 chemokine (C-C motif) ligand 5
CD81 CD81 molecule
COL4A5 collagen, type IV, alpha 5
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
GAS6 growth arrest-specific 6
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
LBH limb bud and heart development
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
RGS4 regulator of G-protein signaling 4
TARP TCR gamma alternate reading frame protein
TUBB4B tubulin, beta 4B class IVb
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
XCL1 chemokine (C motif) ligand 1
Funding