BRD-K45861246_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K45861246_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASPN asporin
CLCA4 chloride channel accessory 4
COL11A1 collagen, type XI, alpha 1
CTNND1 catenin (cadherin-associated protein), delta 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM69A family with sequence similarity 69, member A
GAS6 growth arrest-specific 6
GRB7 growth factor receptor-bound protein 7
HIST1H2BD histone cluster 1, H2bd
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PELI1 pellino E3 ubiquitin protein ligase 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
POSTN periostin, osteoblast specific factor
RGCC regulator of cell cycle
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
THBS2 thrombospondin 2
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP7 A kinase (PRKA) anchor protein 7
BASP1 brain abundant, membrane attached signal protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FOXC1 forkhead box C1
HMG20B high mobility group 20B
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SYBU syntabulin (syntaxin-interacting)
TSPAN8 tetraspanin 8