| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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147 genes differentially expressed following the BRD-K46056750_AZD-7762_MDAMB231_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACKR3 | atypical chemokine receptor 3 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALDOC | aldolase C, fructose-bisphosphate |
| B3GNT1 | |
| BEX4 | brain expressed, X-linked 4 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BTG2 | BTG family, member 2 |
| C3 | complement component 3 |
| CCNG2 | cyclin G2 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHRDL1 | chordin-like 1 |
| CTSF | cathepsin F |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHCR24 | 24-dehydrocholesterol reductase |
| ETFB | electron-transfer-flavoprotein, beta polypeptide |
| FADS1 | fatty acid desaturase 1 |
| FAM8A1 | family with sequence similarity 8, member A1 |
| FCGBP | Fc fragment of IgG binding protein |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FOXO4 | forkhead box O4 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GOLGA8A | golgin A8 family, member A |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPB8 | heat shock 22kDa protein 8 |
| IRS2 | insulin receptor substrate 2 |
| ITM2C | integral membrane protein 2C |
| KDM3A | lysine (K)-specific demethylase 3A |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIZ | kizuna centrosomal protein |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LUM | lumican |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAGED1 | melanoma antigen family D1 |
| MAGED2 | melanoma antigen family D2 |
| MXRA5 | matrix-remodelling associated 5 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) |
| NNMT | nicotinamide N-methyltransferase |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OLFML3 | olfactomedin-like 3 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PRKCQ | protein kinase C, theta |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| SALL2 | spalt-like transcription factor 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SSPN | sarcospan |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULF1 | sulfatase 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM59 | transmembrane protein 59 |
| TPP1 | tripeptidyl peptidase I |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPAN13 | tetraspanin 13 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| WBP5 | WW domain binding protein 5 |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| AIM1 | absent in melanoma 1 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ASF1B | anti-silencing function 1B histone chaperone |
| AURKB | aurora kinase B |
| BOP1 | block of proliferation 1 |
| BZW2 | basic leucine zipper and W2 domains 2 |
| CALML5 | calmodulin-like 5 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CBR3 | carbonyl reductase 3 |
| CCNA2 | cyclin A2 |
| CCND1 | cyclin D1 |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CLDN3 | claudin 3 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CTPS1 | CTP synthase 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DBF4 | DBF4 zinc finger |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EFHD1 | EF-hand domain family, member D1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| FAM129A | family with sequence similarity 129, member A |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| GAL | galanin/GMAP prepropeptide |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| HMGA1 | high mobility group AT-hook 1 |
| KIAA0020 | KIAA0020 |
| KRT14 | keratin 14, type I |
| LMNB1 | lamin B1 |
| LMNB2 | lamin B2 |
| LTF | lactotransferrin |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MELK | maternal embryonic leucine zipper kinase |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAV3 | neuron navigator 3 |
| PCNA | proliferating cell nuclear antigen |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLAC8 | placenta-specific 8 |
| PLK1 | polo-like kinase 1 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| PPIF | peptidylprolyl isomerase F |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RANBP1 | RAN binding protein 1 |
| RCC1 | regulator of chromosome condensation 1 |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RGS4 | regulator of G-protein signaling 4 |
| RRM2 | ribonucleotide reductase M2 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPP1 | secreted phosphoprotein 1 |
| SRM | spermidine synthase |
| TPX2 | TPX2, microtubule-associated |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| UCK2 | uridine-cytidine kinase 2 |
| USP1 | ubiquitin specific peptidase 1 |
| ZWINT | ZW10 interacting kinetochore protein |
