BRD-K46531780_Methyl benzethonium chloride_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K46531780_Methyl benzethonium chloride_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
CARKD carbohydrate kinase domain containing
DHRS2 dehydrogenase/reductase (SDR family) member 2
DOK5 docking protein 5
EGR1 early growth response 1
EPCAM epithelial cell adhesion molecule
FABP4 fatty acid binding protein 4, adipocyte
GHR growth hormone receptor
GREM1 gremlin 1, DAN family BMP antagonist
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IL11RA interleukin 11 receptor, alpha
IL6 interleukin 6
INSIG1 insulin induced gene 1
JAM2 junctional adhesion molecule 2
JUNB jun B proto-oncogene
KLF2 Kruppel-like factor 2
LDLR low density lipoprotein receptor
LEPR leptin receptor
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
PCGF2 polycomb group ring finger 2
PSPH phosphoserine phosphatase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP1 retinol binding protein 1, cellular
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERINC5 serine incorporator 5
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1

decreased expression

Symbol Name
ATF5 activating transcription factor 5
CCL5 chemokine (C-C motif) ligand 5
CD8A CD8a molecule
CXCL13 chemokine (C-X-C motif) ligand 13
GNLY granulysin
GTPBP8 GTP-binding protein 8 (putative)
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HIST1H4C histone cluster 1, H4c
HOPX HOP homeobox
HSPA1A heat shock 70kDa protein 1A
IDO1 indoleamine 2,3-dioxygenase 1
IL2RB interleukin 2 receptor, beta
KIAA1033 KIAA1033
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NT5DC2 5'-nucleotidase domain containing 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TATDN2 TatD DNase domain containing 2
TFPI2 tissue factor pathway inhibitor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)