| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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134 genes differentially expressed following the BRD-K47659338_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| AMACR | alpha-methylacyl-CoA racemase |
| AMDHD2 | amidohydrolase domain containing 2 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOD | apolipoprotein D |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| BAG2 | BCL2-associated athanogene 2 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CD320 | CD320 molecule |
| CES1 | carboxylesterase 1 |
| CPD | carboxypeptidase D |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
| DUSP22 | dual specificity phosphatase 22 |
| EGR3 | early growth response 3 |
| EML3 | echinoderm microtubule associated protein like 3 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FADS1 | fatty acid desaturase 1 |
| FAS | Fas cell surface death receptor |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GPX3 | glutathione peroxidase 3 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| HOXC6 | homeobox C6 |
| INTS3 | integrator complex subunit 3 |
| ITM2A | integral membrane protein 2A |
| KANK2 | KN motif and ankyrin repeat domains 2 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
| KIF14 | kinesin family member 14 |
| LY75 | lymphocyte antigen 75 |
| MYO10 | myosin X |
| NOV | nephroblastoma overexpressed |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OPN3 | opsin 3 |
| PDLIM5 | PDZ and LIM domain 5 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLA1A | phospholipase A1 member A |
| PLCB4 | phospholipase C, beta 4 |
| PRUNE | prune exopolyphosphatase |
| PURA | purine-rich element binding protein A |
| QPCT | glutaminyl-peptide cyclotransferase |
| RBPMS | RNA binding protein with multiple splicing |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SORD | sorbitol dehydrogenase |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
| TNIK | TRAF2 and NCK interacting kinase |
| TPD52L1 | tumor protein D52-like 1 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF451 | zinc finger protein 451 |
| Symbol | Name |
|---|---|
| ADAMDEC1 | ADAM-like, decysin 1 |
| ADIRF | adipogenesis regulatory factor |
| ADM | adrenomedullin |
| ANPEP | alanyl (membrane) aminopeptidase |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C1QA | complement component 1, q subcomponent, A chain |
| CA1 | carbonic anhydrase I |
| CA2 | carbonic anhydrase II |
| CALML3 | calmodulin-like 3 |
| CANT1 | calcium activated nucleotidase 1 |
| CD24 | CD24 molecule |
| CD9 | CD9 molecule |
| CLEC2B | C-type lectin domain family 2, member B |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CST7 | cystatin F (leukocystatin) |
| CSTA | cystatin A (stefin A) |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DENND1B | DENN/MADD domain containing 1B |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide |
| EFS | embryonal Fyn-associated substrate |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FHL1 | four and a half LIM domains 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FXYD6 | FXYD domain containing ion transport regulator 6 |
| GATA3 | GATA binding protein 3 |
| HBB | hemoglobin, beta |
| HOPX | HOP homeobox |
| HOXD1 | homeobox D1 |
| IER3 | immediate early response 3 |
| ITGA6 | integrin, alpha 6 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KRT14 | keratin 14, type I |
| KRT5 | keratin 5, type II |
| KRT6B | keratin 6B, type II |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LYZ | lysozyme |
| MFAP2 | microfibrillar-associated protein 2 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MT1E | metallothionein 1E |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| NLRP2 | NLR family, pyrin domain containing 2 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PTHLH | parathyroid hormone-like hormone |
| PXDN | peroxidasin |
| RGCC | regulator of cell cycle |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RTN2 | reticulon 2 |
| S100A14 | S100 calcium binding protein A14 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRR1B | small proline-rich protein 1B |
| STAB1 | stabilin 1 |
| SULF1 | sulfatase 1 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TMEM45A | transmembrane protein 45A |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRIM29 | tripartite motif containing 29 |
| TUBB2A | tubulin, beta 2A class IIa |
| TYROBP | TYRO protein tyrosine kinase binding protein |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
