| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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96 genes differentially expressed following the BRD-K47869605_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AHSP | alpha hemoglobin stabilizing protein |
| ALAS2 | 5'-aminolevulinate synthase 2 |
| ANXA3 | annexin A3 |
| CALD1 | caldesmon 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| EGFR | epidermal growth factor receptor |
| EXT1 | exostosin glycosyltransferase 1 |
| FHL2 | four and a half LIM domains 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| INHBB | inhibin, beta B |
| JUN | jun proto-oncogene |
| KIAA1033 | KIAA1033 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLK11 | kallikrein-related peptidase 11 |
| KRT14 | keratin 14, type I |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MT1X | metallothionein 1X |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| P3H2 | prolyl 3-hydroxylase 2 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDLIM5 | PDZ and LIM domain 5 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PPOX | protoporphyrinogen oxidase |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| RGS4 | regulator of G-protein signaling 4 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TXNIP | thioredoxin interacting protein |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AHR | aryl hydrocarbon receptor |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| CCND1 | cyclin D1 |
| CHGB | chromogranin B |
| CIRBP | cold inducible RNA binding protein |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DCLK1 | doublecortin-like kinase 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP6 | dual specificity phosphatase 6 |
| EDNRB | endothelin receptor type B |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| EXOSC4 | exosome component 4 |
| FHL1 | four and a half LIM domains 1 |
| FZD7 | frizzled class receptor 7 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2BK | histone cluster 1, H2bk |
| HSPA1A | heat shock 70kDa protein 1A |
| IER3 | immediate early response 3 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MARCKSL1 | MARCKS-like 1 |
| MDK | midkine (neurite growth-promoting factor 2) |
| METRN | meteorin, glial cell differentiation regulator |
| MFSD10 | major facilitator superfamily domain containing 10 |
| NPY1R | neuropeptide Y receptor Y1 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| OLFM1 | olfactomedin 1 |
| PIR | pirin (iron-binding nuclear protein) |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB13 | RAB13, member RAS oncogene family |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCG2 | secretogranin II |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SRPX | sushi-repeat containing protein, X-linked |
| SRSF9 | serine/arginine-rich splicing factor 9 |
| TFF1 | trefoil factor 1 |
| THBS1 | thrombospondin 1 |
| TSPAN13 | tetraspanin 13 |
| TSPAN8 | tetraspanin 8 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZMAT3 | zinc finger, matrin-type 3 |
