Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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116 genes differentially expressed following the BRD-K49328571_dasatinib_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1C3 | aldo-keto reductase family 1, member C3 |
AMDHD2 | amidohydrolase domain containing 2 |
APP | amyloid beta (A4) precursor protein |
AQP1 | aquaporin 1 (Colton blood group) |
ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
CD24 | CD24 molecule |
CLU | clusterin |
COCH | cochlin |
CRISP3 | cysteine-rich secretory protein 3 |
CTAG2 | cancer/testis antigen 2 |
CYBA | cytochrome b-245, alpha polypeptide |
DCN | decorin |
DDR1 | discoidin domain receptor tyrosine kinase 1 |
DEFB1 | defensin, beta 1 |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
EFHD1 | EF-hand domain family, member D1 |
EIF5A | eukaryotic translation initiation factor 5A |
FBLN5 | fibulin 5 |
GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
IER3 | immediate early response 3 |
IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
ISG15 | ISG15 ubiquitin-like modifier |
ITGB5 | integrin, beta 5 |
KYNU | kynureninase |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LOC100505650 | uncharacterized LOC100505650 |
LPP | LIM domain containing preferred translocation partner in lipoma |
MAGEA12 | melanoma antigen family A12 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
NCALD | neurocalcin delta |
NOV | nephroblastoma overexpressed |
NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
PRAME | preferentially expressed antigen in melanoma |
RHOB | ras homolog family member B |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
SATB2 | SATB homeobox 2 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
SETBP1 | SET binding protein 1 |
SETD5 | SET domain containing 5 |
SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
SQSTM1 | sequestosome 1 |
STC1 | stanniocalcin 1 |
STK26 | serine/threonine protein kinase 26 |
TATDN2 | TatD DNase domain containing 2 |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
TFPI2 | tissue factor pathway inhibitor 2 |
TNC | tenascin C |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPD52L1 | tumor protein D52-like 1 |
TRPS1 | trichorhinophalangeal syndrome I |
TUSC3 | tumor suppressor candidate 3 |
VDAC1 | voltage-dependent anion channel 1 |
VLDLR | very low density lipoprotein receptor |
VSNL1 | visinin-like 1 |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
WFDC2 | WAP four-disulfide core domain 2 |
ZMYM2 | zinc finger, MYM-type 2 |
Symbol | Name |
---|---|
ADAM9 | ADAM metallopeptidase domain 9 |
ADD3 | adducin 3 (gamma) |
ADGRG2 | adhesion G protein-coupled receptor G2 |
ANPEP | alanyl (membrane) aminopeptidase |
C3ORF14 | chromosome 3 open reading frame 14 |
CA2 | carbonic anhydrase II |
CCDC86 | coiled-coil domain containing 86 |
CCND2 | cyclin D2 |
CD36 | CD36 molecule (thrombospondin receptor) |
COL5A2 | collagen, type V, alpha 2 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DLK1 | delta-like 1 homolog (Drosophila) |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
DUOX2 | dual oxidase 2 |
EGR2 | early growth response 2 |
EIF5 | eukaryotic translation initiation factor 5 |
F2R | coagulation factor II (thrombin) receptor |
FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
FGL2 | fibrinogen-like 2 |
FNTA | farnesyltransferase, CAAX box, alpha |
FSTL1 | follistatin-like 1 |
GTF2A2 | general transcription factor IIA, 2, 12kDa |
GTPBP8 | GTP-binding protein 8 (putative) |
HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
HOPX | HOP homeobox |
HOXB2 | homeobox B2 |
IER5 | immediate early response 5 |
JCHAIN | joining chain of multimeric IgA and IgM |
KLF10 | Kruppel-like factor 10 |
LIMA1 | LIM domain and actin binding 1 |
LPAR1 | lysophosphatidic acid receptor 1 |
LRRC17 | leucine rich repeat containing 17 |
MFAP5 | microfibrillar associated protein 5 |
NNMT | nicotinamide N-methyltransferase |
NPTX2 | neuronal pentraxin II |
PCSK6 | proprotein convertase subtilisin/kexin type 6 |
PEG10 | paternally expressed 10 |
PHACTR2 | phosphatase and actin regulator 2 |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PLIN2 | perilipin 2 |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PSPH | phosphoserine phosphatase |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
PTX3 | pentraxin 3, long |
RBP1 | retinol binding protein 1, cellular |
RGCC | regulator of cell cycle |
SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
THBS2 | thrombospondin 2 |
TIMP3 | TIMP metallopeptidase inhibitor 3 |
TM9SF3 | transmembrane 9 superfamily member 3 |
WBP5 | WW domain binding protein 5 |