Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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68 genes differentially expressed following the BRD-K49669041_BX-912_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALG8 | ALG8, alpha-1,3-glucosyltransferase |
CES1 | carboxylesterase 1 |
CLNS1A | chloride channel, nucleotide-sensitive, 1A |
COL1A1 | collagen, type I, alpha 1 |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EGR3 | early growth response 3 |
ENDOD1 | endonuclease domain containing 1 |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
HDAC6 | histone deacetylase 6 |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
IRX5 | iroquois homeobox 5 |
LGALS3 | lectin, galactoside-binding, soluble, 3 |
LMCD1 | LIM and cysteine-rich domains 1 |
LRRN3 | leucine rich repeat neuronal 3 |
MAMLD1 | mastermind-like domain containing 1 |
MYRF | myelin regulatory factor |
PDZK1 | PDZ domain containing 1 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PON2 | paraoxonase 2 |
SELL | selectin L |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
TM4SF1 | transmembrane 4 L six family member 1 |
TNC | tenascin C |
Symbol | Name |
---|---|
ACTC1 | actin, alpha, cardiac muscle 1 |
AQP1 | aquaporin 1 (Colton blood group) |
CCNG2 | cyclin G2 |
CD24 | CD24 molecule |
CFH | complement factor H |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
CLDN7 | claudin 7 |
CREB1 | cAMP responsive element binding protein 1 |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL11 | chemokine (C-X-C motif) ligand 11 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
FABP4 | fatty acid binding protein 4, adipocyte |
FILIP1L | filamin A interacting protein 1-like |
FXYD3 | FXYD domain containing ion transport regulator 3 |
GBP1 | guanylate binding protein 1, interferon-inducible |
GPX2 | glutathione peroxidase 2 |
GSDMB | gasdermin B |
IFI44L | interferon-induced protein 44-like |
KANK1 | KN motif and ankyrin repeat domains 1 |
KCTD12 | potassium channel tetramerization domain containing 12 |
LYN | LYN proto-oncogene, Src family tyrosine kinase |
MEIS2 | Meis homeobox 2 |
MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
MMP7 | matrix metallopeptidase 7 |
MTERF3 | mitochondrial transcription termination factor 3 |
PDGFD | platelet derived growth factor D |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PLCB4 | phospholipase C, beta 4 |
RGS5 | regulator of G-protein signaling 5 |
SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
SLC38A1 | solute carrier family 38, member 1 |
SP110 | SP110 nuclear body protein |
STAT1 | signal transducer and activator of transcription 1, 91kDa |
SULF1 | sulfatase 1 |
TCF4 | transcription factor 4 |
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TRAPPC3 | trafficking protein particle complex 3 |