BRD-K49669041_BX-912_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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68 genes differentially expressed following the BRD-K49669041_BX-912_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALG8 ALG8, alpha-1,3-glucosyltransferase
CES1 carboxylesterase 1
CLNS1A chloride channel, nucleotide-sensitive, 1A
COL1A1 collagen, type I, alpha 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
ENDOD1 endonuclease domain containing 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
HDAC6 histone deacetylase 6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRX5 iroquois homeobox 5
LGALS3 lectin, galactoside-binding, soluble, 3
LMCD1 LIM and cysteine-rich domains 1
LRRN3 leucine rich repeat neuronal 3
MAMLD1 mastermind-like domain containing 1
MYRF myelin regulatory factor
PDZK1 PDZ domain containing 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PON2 paraoxonase 2
SELL selectin L
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
TM4SF1 transmembrane 4 L six family member 1
TNC tenascin C

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
AQP1 aquaporin 1 (Colton blood group)
CCNG2 cyclin G2
CD24 CD24 molecule
CFH complement factor H
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLDN7 claudin 7
CREB1 cAMP responsive element binding protein 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
FABP4 fatty acid binding protein 4, adipocyte
FILIP1L filamin A interacting protein 1-like
FXYD3 FXYD domain containing ion transport regulator 3
GBP1 guanylate binding protein 1, interferon-inducible
GPX2 glutathione peroxidase 2
GSDMB gasdermin B
IFI44L interferon-induced protein 44-like
KANK1 KN motif and ankyrin repeat domains 1
KCTD12 potassium channel tetramerization domain containing 12
LYN LYN proto-oncogene, Src family tyrosine kinase
MEIS2 Meis homeobox 2
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP7 matrix metallopeptidase 7
MTERF3 mitochondrial transcription termination factor 3
PDGFD platelet derived growth factor D
PECAM1 platelet/endothelial cell adhesion molecule 1
PLCB4 phospholipase C, beta 4
RGS5 regulator of G-protein signaling 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC38A1 solute carrier family 38, member 1
SP110 SP110 nuclear body protein
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TCF4 transcription factor 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRAPPC3 trafficking protein particle complex 3