| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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139 genes differentially expressed following the BRD-K49865102_PD-0325901_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ABHD4 | abhydrolase domain containing 4 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| ALB | albumin |
| APOL1 | apolipoprotein L, 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BCL6 | B-cell CLL/lymphoma 6 |
| BLNK | B-cell linker |
| C3 | complement component 3 |
| C5AR1 | complement component 5a receptor 1 |
| CA12 | carbonic anhydrase XII |
| CD24 | CD24 molecule |
| CFB | complement factor B |
| CLIC5 | chloride intracellular channel 5 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| CSTA | cystatin A (stefin A) |
| DACH1 | dachshund family transcription factor 1 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DSP | desmoplakin |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EMX2 | empty spiracles homeobox 2 |
| FPR1 | formyl peptide receptor 1 |
| FYB | FYN binding protein |
| GLUL | glutamate-ammonia ligase |
| GPX3 | glutathione peroxidase 3 |
| HIST1H2BD | histone cluster 1, H2bd |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HMOX1 | heme oxygenase 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| KRT19 | keratin 19, type I |
| LCN2 | lipocalin 2 |
| LEFTY1 | left-right determination factor 1 |
| LOC100505650 | uncharacterized LOC100505650 |
| LTF | lactotransferrin |
| METTL7A | methyltransferase like 7A |
| MX2 | MX dynamin-like GTPase 2 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| POSTN | periostin, osteoblast specific factor |
| PRKCD | protein kinase C, delta |
| PRUNE2 | prune homolog 2 (Drosophila) |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| S100A8 | S100 calcium binding protein A8 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SELENBP1 | selenium binding protein 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| STK38 | serine/threonine kinase 38 |
| THAP11 | THAP domain containing 11 |
| TLR4 | toll-like receptor 4 |
| TMEM100 | transmembrane protein 100 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNS1 | tensin 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WIF1 | WNT inhibitory factor 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF331 | zinc finger protein 331 |
| Symbol | Name |
|---|---|
| ACD | adrenocortical dysplasia homolog (mouse) |
| AK4 | adenylate kinase 4 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| ANXA3 | annexin A3 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CAB39 | calcium binding protein 39 |
| CALML5 | calmodulin-like 5 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCND1 | cyclin D1 |
| CD44 | CD44 molecule (Indian blood group) |
| CD81 | CD81 molecule |
| CDC42 | cell division cycle 42 |
| CSRP1 | cysteine and glycine-rich protein 1 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EGFR | epidermal growth factor receptor |
| EGR3 | early growth response 3 |
| ENO1 | enolase 1, (alpha) |
| ETV1 | ets variant 1 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FLNA | filamin A, alpha |
| FOSL1 | FOS-like antigen 1 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| ITGB5 | integrin, beta 5 |
| JUN | jun proto-oncogene |
| KRT6B | keratin 6B, type II |
| LYPLA1 | lysophospholipase I |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| NFIB | nuclear factor I/B |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OLA1 | Obg-like ATPase 1 |
| PFKP | phosphofructokinase, platelet |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLK2 | polo-like kinase 2 |
| PMP22 | peripheral myelin protein 22 |
| PON3 | paraoxonase 3 |
| PPA1 | pyrophosphatase (inorganic) 1 |
| PRDX4 | peroxiredoxin 4 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTRF | polymerase I and transcript release factor |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| SFRP1 | secreted frizzled-related protein 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) |
| SYNJ2 | synaptojanin 2 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TUBB2A | tubulin, beta 2A class IIa |
| UPP1 | uridine phosphorylase 1 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
