BRD-K49865102_PD-0325901_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

666 genes differentially expressed following the BRD-K49865102_PD-0325901_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ABAT 4-aminobutyrate aminotransferase
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ACPP acid phosphatase, prostate
ACSL1 acyl-CoA synthetase long-chain family member 1
ADD3 adducin 3 (gamma)
ADRB2 adrenoceptor beta 2, surface
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AMACR alpha-methylacyl-CoA racemase
AMDHD2 amidohydrolase domain containing 2
ANXA4 annexin A4
ARHGAP29 Rho GTPase activating protein 29
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARMCX1 armadillo repeat containing, X-linked 1
ARMCX3 armadillo repeat containing, X-linked 3
ARMCX6 armadillo repeat containing, X-linked 6
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAMBI BMP and activin membrane-bound inhibitor
BECN1 beclin 1, autophagy related
BLVRA biliverdin reductase A
BLVRB biliverdin reductase B
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BPIFA1 BPI fold containing family A, member 1
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
C5 complement component 5
CA12 carbonic anhydrase XII
CAPN1 calpain 1, (mu/I) large subunit
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAT catalase
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CELF2 CUGBP, Elav-like family member 2
CETN2 centrin, EF-hand protein, 2
CFB complement factor B
CFI complement factor I
CLGN calmegin
CLNS1A chloride channel, nucleotide-sensitive, 1A
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A1 collagen, type I, alpha 1
COL4A5 collagen, type IV, alpha 5
COL5A1 collagen, type V, alpha 1
CP ceruloplasmin (ferroxidase)
CPD carboxypeptidase D
CRYAB crystallin, alpha B
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
CTBP2 C-terminal binding protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSA cathepsin A
CXCL5 chemokine (C-X-C motif) ligand 5
CYB5A cytochrome b5 type A (microsomal)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDR1 discoidin domain receptor tyrosine kinase 1
DEFB1 defensin, beta 1
DHCR24 24-dehydrocholesterol reductase
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DPP4 dipeptidyl-peptidase 4
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
DYNLRB1 dynein, light chain, roadblock-type 1
E2F2 E2F transcription factor 2
EFNA1 ephrin-A1
EGFL6 EGF-like-domain, multiple 6
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELOVL5 ELOVL fatty acid elongase 5
EML3 echinoderm microtubule associated protein like 3
EMP2 epithelial membrane protein 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
F13A1 coagulation factor XIII, A1 polypeptide
FADS3 fatty acid desaturase 3
FAM114A1 family with sequence similarity 114, member A1
FAM134B family with sequence similarity 134, member B
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FASN fatty acid synthase
FBLN1 fibulin 1
FBN2 fibrillin 2
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FGL1 fibrinogen-like 1
FHL1 four and a half LIM domains 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FOSL2 FOS-like antigen 2
FXYD2 FXYD domain containing ion transport regulator 2
FXYD3 FXYD domain containing ion transport regulator 3
GAB2 GRB2-associated binding protein 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GATA2 GATA binding protein 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GC group-specific component (vitamin D binding protein)
GJA1 gap junction protein, alpha 1, 43kDa
GLOD4 glyoxalase domain containing 4
GLUL glutamate-ammonia ligase
GNAS GNAS complex locus
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPX2 glutathione peroxidase 2
GRB14 growth factor receptor-bound protein 14
GSN gelsolin
GSTA1 glutathione S-transferase alpha 1
GSTM3 glutathione S-transferase mu 3 (brain)
H1F0 H1 histone family, member 0
H2BFS H2B histone family, member S (pseudogene)
HAB1 B1 for mucin
HBB hemoglobin, beta
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HGD homogentisate 1,2-dioxygenase
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HP haptoglobin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDI1 isopentenyl-diphosphate delta isomerase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1B interleukin 1, beta
INHBB inhibin, beta B
IRF9 interferon regulatory factor 9
JUP junction plakoglobin
KDM3A lysine (K)-specific demethylase 3A
KRT5 keratin 5, type II
LAMP2 lysosomal-associated membrane protein 2
LBP lipopolysaccharide binding protein
LCN2 lipocalin 2
LDOC1 leucine zipper, down-regulated in cancer 1
LEF1 lymphoid enhancer-binding factor 1
LEPROT leptin receptor overlapping transcript
LGALS8 lectin, galactoside-binding, soluble, 8
LTF lactotransferrin
LXN latexin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGED2 melanoma antigen family D2
MAPT microtubule-associated protein tau
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MGST3 microsomal glutathione S-transferase 3
MME membrane metallo-endopeptidase
MSLN mesothelin
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MVP major vault protein
MXI1 MAX interactor 1, dimerization protein
MXRA5 matrix-remodelling associated 5
MYL9 myosin, light chain 9, regulatory
MYLIP myosin regulatory light chain interacting protein
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NDRG1 N-myc downstream regulated 1
NDRG3 NDRG family member 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEBL nebulette
NEFH neurofilament, heavy polypeptide
NEU1 sialidase 1 (lysosomal sialidase)
NFIL3 nuclear factor, interleukin 3 regulated
NNMT nicotinamide N-methyltransferase
NOTCH1 notch 1
NOV nephroblastoma overexpressed
NPC2 Niemann-Pick disease, type C2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUPR1 nuclear protein, transcriptional regulator, 1
NXN nucleoredoxin
OLFML2B olfactomedin-like 2B
OPTN optineurin
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBLD phenazine biosynthesis-like protein domain containing
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCP4 Purkinje cell protein 4
PDGFD platelet derived growth factor D
PDZD2 PDZ domain containing 2
PDZK1IP1 PDZK1 interacting protein 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PENK proenkephalin
PERP PERP, TP53 apoptosis effector
PHACTR2 phosphatase and actin regulator 2
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIR pirin (iron-binding nuclear protein)
PKP2 plakophilin 2
PLA2G16 phospholipase A2, group XVI
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEK pleckstrin
PLIN2 perilipin 2
PLSCR3 phospholipid scramblase 3
PON2 paraoxonase 2
PPAP2A phosphatidic acid phosphatase type 2A
PPL periplakin
PROM1 prominin 1
PRSS23 protease, serine, 23
PRUNE prune exopolyphosphatase
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PXDN peroxidasin
QPRT quinolinate phosphoribosyltransferase
RAB6A RAB6A, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBM15B RNA binding motif protein 15B
RCAN1 regulator of calcineurin 1
REEP1 receptor accessory protein 1
RHOB ras homolog family member B
RHOQ ras homolog family member Q
RIT1 Ras-like without CAAX 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A10 S100 calcium binding protein A10
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAT1 spermidine/spermine N1-acetyltransferase 1
SC5D sterol-C5-desaturase
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCN3A sodium channel, voltage gated, type III alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEC31A SEC31 homolog A (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SELENBP1 selenium binding protein 1
SERINC5 serine incorporator 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SGMS1 sphingomyelin synthase 1
SH3BGR SH3 domain binding glutamate-rich protein
SH3YL1 SH3 and SYLF domain containing 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLPI secretory leukocyte peptidase inhibitor
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORD sorbitol dehydrogenase
SPAG4 sperm associated antigen 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPON2 spondin 2, extracellular matrix protein
SQLE squalene epoxidase
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAB1 stabilin 1
STOM stomatin
SULF1 sulfatase 1
SYBU syntabulin (syntaxin-interacting)
SYNE2 spectrin repeat containing, nuclear envelope 2
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TGFBI transforming growth factor, beta-induced, 68kDa
THSD7A thrombospondin, type I, domain containing 7A
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM59 transmembrane protein 59
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNC1 troponin C type 1 (slow)
TOX3 TOX high mobility group box family member 3
TPM2 tropomyosin 2 (beta)
TPP1 tripeptidyl peptidase I
TRIM16 tripartite motif containing 16
TRIM29 tripartite motif containing 29
TSC22D1 TSC22 domain family, member 1
TSPAN13 tetraspanin 13
TTC39A tetratricopeptide repeat domain 39A
TYMP thymidine phosphorylase
UBXN4 UBX domain protein 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
USP6NL USP6 N-terminal like
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAT1 vesicle amine transport 1
VAV3 vav 3 guanine nucleotide exchange factor
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1
WDTC1 WD and tetratricopeptide repeats 1
WFDC2 WAP four-disulfide core domain 2
WFS1 Wolfram syndrome 1 (wolframin)
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1
YPEL5 yippee-like 5 (Drosophila)
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
AK4 adenylate kinase 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANXA1 annexin A1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARMCX2 armadillo repeat containing, X-linked 2
ASF1B anti-silencing function 1B histone chaperone
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAD2 ATPase family, AAA domain containing 2
AUNIP aurora kinase A and ninein interacting protein
AURKA aurora kinase A
AURKB aurora kinase B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BARD1 BRCA1 associated RING domain 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIRC5 baculoviral IAP repeat containing 5
BPHL biphenyl hydrolase-like (serine hydrolase)
BRCA1 breast cancer 1, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C1QBP complement component 1, q subcomponent binding protein
C6ORF62 chromosome 6 open reading frame 62
C7 complement component 7
CCDC85B coiled-coil domain containing 85B
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CCNB2 cyclin B2
CCND1 cyclin D1
CCNF cyclin F
CD83 CD83 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDC7 cell division cycle 7
CDCA4 cell division cycle associated 4
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CDT1 chromatin licensing and DNA replication factor 1
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPN centromere protein N
CENPU centromere protein U
CEP55 centrosomal protein 55kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLC Charcot-Leyden crystal galectin
COL10A1 collagen, type X, alpha 1
COMP cartilage oligomeric matrix protein
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CSRP1 cysteine and glycine-rich protein 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTPS1 CTP synthase 1
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYTL1 cytokine-like 1
DBF4 DBF4 zinc finger
DHFR dihydrofolate reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLC1 DLC1 Rho GTPase activating protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLK1 delta-like 1 homolog (Drosophila)
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DSCC1 DNA replication and sister chromatid cohesion 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DUT deoxyuridine triphosphatase
ECT2 epithelial cell transforming 2
EGR2 early growth response 2
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5 eukaryotic translation initiation factor 5
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ETV1 ets variant 1
ETV4 ets variant 4
ETV5 ets variant 5
EXO1 exonuclease 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129A family with sequence similarity 129, member A
FAM46A family with sequence similarity 46, member A
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FBP1 fructose-1,6-bisphosphatase 1
FEN1 flap structure-specific endonuclease 1
FERMT1 fermitin family member 1
FGF13 fibroblast growth factor 13
FGFR3 fibroblast growth factor receptor 3
FJX1 four jointed box 1 (Drosophila)
FKBP14 FK506 binding protein 14, 22 kDa
FKSG49 FKSG49
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
FRZB frizzled-related protein
FST follistatin
FXYD6 FXYD domain containing ion transport regulator 6
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GEM GTP binding protein overexpressed in skeletal muscle
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMNN geminin, DNA replication inhibitor
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GTSE1 G-2 and S-phase expressed 1
GUSBP3 glucuronidase, beta pseudogene 3
H2AFX H2A histone family, member X
HAT1 histone acetyltransferase 1
HBEGF heparin-binding EGF-like growth factor
HELLS helicase, lymphoid-specific
HEPH hephaestin
HHEX hematopoietically expressed homeobox
HIST1H2BG histone cluster 1, H2bg
HIST1H4C histone cluster 1, H4c
HJURP Holliday junction recognition protein
HK2 hexokinase 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HNRNPL heterogeneous nuclear ribonucleoprotein L
HOPX HOP homeobox
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HTRA1 HtrA serine peptidase 1
IER2 immediate early response 2
IER3 immediate early response 3
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL13RA2 interleukin 13 receptor, alpha 2
IPO13 importin 13
ISOC1 isochorismatase domain containing 1
ITM2A integral membrane protein 2A
ITPKB inositol-trisphosphate 3-kinase B
JADE2 jade family PHD finger 2
KCTD12 potassium channel tetramerization domain containing 12
KIAA0101 KIAA0101
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KIF15 kinesin family member 15
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF4A kinesin family member 4A
LAMP5 lysosomal-associated membrane protein family, member 5
LIG1 ligase I, DNA, ATP-dependent
LMNB1 lamin B1
LMO3 LIM domain only 3 (rhombotin-like 2)
LMO4 LIM domain only 4
LPAR1 lysophosphatidic acid receptor 1
MACF1 microtubule-actin crosslinking factor 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARCKS myristoylated alanine-rich protein kinase C substrate
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MELK maternal embryonic leucine zipper kinase
MGLL monoglyceride lipase
MGP matrix Gla protein
MINA MYC induced nuclear antigen
MKI67 marker of proliferation Ki-67
MMP12 matrix metallopeptidase 12
MPO myeloperoxidase
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MT1E metallothionein 1E
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAV3 neuron navigator 3
NCAM1 neural cell adhesion molecule 1
NCAPG non-SMC condensin I complex, subunit G
NCAPG2 non-SMC condensin II complex, subunit G2
NCAPH non-SMC condensin I complex, subunit H
NDC80 NDC80 kinetochore complex component
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NELL2 NEL-like 2 (chicken)
NET1 neuroepithelial cell transforming 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFIB nuclear factor I/B
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP56 NOP56 ribonucleoprotein
NPAS2 neuronal PAS domain protein 2
NPTX1 neuronal pentraxin I
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OLFM1 olfactomedin 1
ORC1 origin recognition complex, subunit 1
ORC6 origin recognition complex, subunit 6
PADI2 peptidyl arginine deiminase, type II
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PBK PDZ binding kinase
PCNA proliferating cell nuclear antigen
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM1 PDZ and LIM domain 1
PDLIM3 PDZ and LIM domain 3
PDLIM4 PDZ and LIM domain 4
PEG3 paternally expressed 3
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PLK1 polo-like kinase 1
PMP22 peripheral myelin protein 22
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPAT phosphoribosyl pyrophosphate amidotransferase
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PROSC proline synthetase co-transcribed homolog (bacterial)
PRPF4 pre-mRNA processing factor 4
PRSS3 protease, serine, 3
PSPH phosphoserine phosphatase
PSRC1 proline/serine-rich coiled-coil 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PTX3 pentraxin 3, long
PUS7 pseudouridylate synthase 7 (putative)
RAB20 RAB20, member RAS oncogene family
RACGAP1 Rac GTPase activating protein 1
RAD21 RAD21 homolog (S. pombe)
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD51C RAD51 paralog C
RANBP1 RAN binding protein 1
RAP1GAP RAP1 GTPase activating protein
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTN1 reticulon 1
SATB2 SATB homeobox 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC43A3 solute carrier family 43, member 3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMC2 structural maintenance of chromosomes 2
SNAI2 snail family zinc finger 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
SPC25 SPC25, NDC80 kinetochore complex component
SPRED2 sprouty-related, EVH1 domain containing 2
SPRR3 small proline-rich protein 3
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRPX2 sushi-repeat containing protein, X-linked 2
SRSF2 serine/arginine-rich splicing factor 2
SRSF6 serine/arginine-rich splicing factor 6
SSRP1 structure specific recognition protein 1
STX1A syntaxin 1A (brain)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TACC3 transforming, acidic coiled-coil containing protein 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFDP1 transcription factor Dp-1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMELESS timeless circadian clock
TK1 thymidine kinase 1, soluble
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM194A transmembrane protein 194A
TMEM97 transmembrane protein 97
TMPO thymopoietin
TMX1 thioredoxin-related transmembrane protein 1
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
TRIP13 thyroid hormone receptor interactor 13
TSPAN4 tetraspanin 4
TYMS thymidylate synthetase
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2S ubiquitin-conjugating enzyme E2S
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UNG uracil-DNA glycosylase
UPP1 uridine phosphorylase 1
USP1 ubiquitin specific peptidase 1
VCAN versican
VRK1 vaccinia related kinase 1
WARS tryptophanyl-tRNA synthetase
WEE1 WEE1 G2 checkpoint kinase
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZFPM2 zinc finger protein, FOG family member 2
ZNF395 zinc finger protein 395
ZNF721 zinc finger protein 721
ZWINT ZW10 interacting kinetochore protein
Funding