| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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238 genes differentially expressed following the BRD-K49865102_PD-0325901_HS578T_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ABLIM1 | actin binding LIM protein 1 |
| ADA | adenosine deaminase |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ANXA4 | annexin A4 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMCX6 | armadillo repeat containing, X-linked 6 |
| ASPN | asporin |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BCL2A1 | BCL2-related protein A1 |
| BST2 | bone marrow stromal cell antigen 2 |
| CA12 | carbonic anhydrase XII |
| CD14 | CD14 molecule |
| CD300A | CD300a molecule |
| CD47 | CD47 molecule |
| CD58 | CD58 molecule |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRYAB | crystallin, alpha B |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CYB561 | cytochrome b561 |
| DCN | decorin |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DSP | desmoplakin |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP22 | dual specificity phosphatase 22 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM8A1 | family with sequence similarity 8, member A1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOLR1 | folate receptor 1 (adult) |
| FTH1 | ferritin, heavy polypeptide 1 |
| G0S2 | G0/G1 switch 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GOLGA8A | golgin A8 family, member A |
| GPX3 | glutathione peroxidase 3 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HBD | hemoglobin, delta |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HSPB8 | heat shock 22kDa protein 8 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IFT57 | intraflagellar transport 57 |
| IL32 | interleukin 32 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KRT14 | keratin 14, type I |
| KRT18 | keratin 18, type I |
| KRT23 | keratin 23, type I |
| LAMA3 | laminin, alpha 3 |
| LAMC2 | laminin, gamma 2 |
| LDLR | low density lipoprotein receptor |
| LEPR | leptin receptor |
| LUM | lumican |
| MAGED2 | melanoma antigen family D2 |
| MAOB | monoamine oxidase B |
| MEIS2 | Meis homeobox 2 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MME | membrane metallo-endopeptidase |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1M | metallothionein 1M |
| MTSS1 | metastasis suppressor 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NEFH | neurofilament, heavy polypeptide |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NXN | nucleoredoxin |
| OXTR | oxytocin receptor |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PDIA5 | protein disulfide isomerase family A, member 5 |
| PENK | proenkephalin |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBP1 | retinol binding protein 1, cellular |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| REEP1 | receptor accessory protein 1 |
| RGCC | regulator of cell cycle |
| RHOB | ras homolog family member B |
| RHOQ | ras homolog family member Q |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RRAGD | Ras-related GTP binding D |
| S100A8 | S100 calcium binding protein A8 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SELENBP1 | selenium binding protein 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNX11 | sorting nexin 11 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPP1 | secreted phosphoprotein 1 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STC2 | stanniocalcin 2 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TNS1 | tensin 1 |
| TPD52L1 | tumor protein D52-like 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPAN7 | tetraspanin 7 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| VWA8 | von Willebrand factor A domain containing 8 |
| XIST | X inactive specific transcript (non-protein coding) |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF423 | zinc finger protein 423 |
| Symbol | Name |
|---|---|
| AIM1 | absent in melanoma 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ASF1B | anti-silencing function 1B histone chaperone |
| AURKB | aurora kinase B |
| BRCA1 | breast cancer 1, early onset |
| CANT1 | calcium activated nucleotidase 1 |
| CCNA2 | cyclin A2 |
| CCNB1 | cyclin B1 |
| CCND1 | cyclin D1 |
| CCNF | cyclin F |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDCA3 | cell division cycle associated 3 |
| CDCA4 | cell division cycle associated 4 |
| CDK1 | cyclin-dependent kinase 1 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CENPU | centromere protein U |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) |
| CHEK2 | checkpoint kinase 2 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| CLTB | clathrin, light chain B |
| COPS7A | COP9 signalosome subunit 7A |
| CRISP3 | cysteine-rich secretory protein 3 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCK | deoxycytidine kinase |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DHFR | dihydrofolate reductase |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUOX2 | dual oxidase 2 |
| DUSP6 | dual specificity phosphatase 6 |
| DUT | deoxyuridine triphosphatase |
| EIF5A | eukaryotic translation initiation factor 5A |
| EMP1 | epithelial membrane protein 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| EREG | epiregulin |
| ETV1 | ets variant 1 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| FANCI | Fanconi anemia, complementation group I |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| FOXM1 | forkhead box M1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| H2AFX | H2A histone family, member X |
| HJURP | Holliday junction recognition protein |
| HMGA1 | high mobility group AT-hook 1 |
| IFRD2 | interferon-related developmental regulator 2 |
| IL1R2 | interleukin 1 receptor, type II |
| ITGB1BP1 | integrin beta 1 binding protein 1 |
| JADE2 | jade family PHD finger 2 |
| KIAA0101 | KIAA0101 |
| KIF18B | kinesin family member 18B |
| KIF1BP | KIF1 binding protein |
| KRT6B | keratin 6B, type II |
| LIG1 | ligase I, DNA, ATP-dependent |
| LOC283683 | uncharacterized LOC283683 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MELK | maternal embryonic leucine zipper kinase |
| MSH2 | mutS homolog 2 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NET1 | neuroepithelial cell transforming 1 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NPTX1 | neuronal pentraxin I |
| NPTX2 | neuronal pentraxin II |
| NUP85 | nucleoporin 85kDa |
| PCNA | proliferating cell nuclear antigen |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PLAU | plasminogen activator, urokinase |
| PRC1 | protein regulator of cytokinesis 1 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PSCA | prostate stem cell antigen |
| RAD51AP1 | RAD51 associated protein 1 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RNASEH2A | ribonuclease H2, subunit A |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| S100P | S100 calcium binding protein P |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STC1 | stanniocalcin 1 |
| STX1A | syntaxin 1A (brain) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TFAM | transcription factor A, mitochondrial |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TIMELESS | timeless circadian clock |
| TLR4 | toll-like receptor 4 |
| TMEM194A | transmembrane protein 194A |
| TNPO1 | transportin 1 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSPAN8 | tetraspanin 8 |
| TSPYL5 | TSPY-like 5 |
| TYMS | thymidylate synthetase |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| VRK1 | vaccinia related kinase 1 |
| ZWINT | ZW10 interacting kinetochore protein |
