| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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129 genes differentially expressed following the BRD-K50140147_NVP-TAE684_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AHR | aryl hydrocarbon receptor |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANXA4 | annexin A4 |
| C14ORF159 | chromosome 14 open reading frame 159 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CLDN18 | claudin 18 |
| CTSH | cathepsin H |
| DAPK1 | death-associated protein kinase 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DYNLT3 | dynein, light chain, Tctex-type 3 |
| EDN1 | endothelin 1 |
| EFNA1 | ephrin-A1 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| FOLR1 | folate receptor 1 (adult) |
| FOXO4 | forkhead box O4 |
| GAB2 | GRB2-associated binding protein 2 |
| GLS | glutaminase |
| GLTSCR2 | glioma tumor suppressor candidate region gene 2 |
| GOLGA8H | golgin A8 family, member H |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPB8 | heat shock 22kDa protein 8 |
| IDS | iduronate 2-sulfatase |
| IRS2 | insulin receptor substrate 2 |
| ISG15 | ISG15 ubiquitin-like modifier |
| JUP | junction plakoglobin |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| LIMCH1 | LIM and calponin homology domains 1 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MFAP5 | microfibrillar associated protein 5 |
| MGST3 | microsomal glutathione S-transferase 3 |
| MVP | major vault protein |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSBPL1A | oxysterol binding protein-like 1A |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLA2G16 | phospholipase A2, group XVI |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| RAP1GAP | RAP1 GTPase activating protein |
| RBKS | ribokinase |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| SFXN3 | sideroflexin 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPATA20 | spermatogenesis associated 20 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| STXBP1 | syntaxin binding protein 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TOX3 | TOX high mobility group box family member 3 |
| TPP1 | tripeptidyl peptidase I |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| TUBA1A | tubulin, alpha 1a |
| TXNIP | thioredoxin interacting protein |
| VAMP8 | vesicle-associated membrane protein 8 |
| VAT1 | vesicle amine transport 1 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AURKA | aurora kinase A |
| BARD1 | BRCA1 associated RING domain 1 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BIRC5 | baculoviral IAP repeat containing 5 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| COL3A1 | collagen, type III, alpha 1 |
| COL6A2 | collagen, type VI, alpha 2 |
| CPE | carboxypeptidase E |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DBF4 | DBF4 zinc finger |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GRB14 | growth factor receptor-bound protein 14 |
| HMGB2 | high mobility group box 2 |
| HSPA14 | heat shock 70kDa protein 14 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGL | immunoglobulin lambda locus |
| KIF4A | kinesin family member 4A |
| KRT15 | keratin 15, type I |
| LTF | lactotransferrin |
| MCM10 | minichromosome maintenance complex component 10 |
| MMP9 | matrix metallopeptidase 9 |
| NEK2 | NIMA-related kinase 2 |
| NES | nestin |
| NID2 | nidogen 2 (osteonidogen) |
| ODC1 | ornithine decarboxylase 1 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PAK1IP1 | PAK1 interacting protein 1 |
| PBK | PDZ binding kinase |
| PDLIM3 | PDZ and LIM domain 3 |
| PFN2 | profilin 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLK1 | polo-like kinase 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SMAD1 | SMAD family member 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) |
