| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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95 genes differentially expressed following the BRD-K50168500_canertinib_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| COL3A1 | collagen, type III, alpha 1 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DACH1 | dachshund family transcription factor 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GPM6B | glycoprotein M6B |
| GRB10 | growth factor receptor-bound protein 10 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM1 | interferon induced transmembrane protein 1 |
| ITM2A | integral membrane protein 2A |
| KRT5 | keratin 5, type II |
| LSM1 | LSM1, U6 small nuclear RNA associated |
| MECOM | MDS1 and EVI1 complex locus |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MMP10 | matrix metallopeptidase 10 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MUC16 | mucin 16, cell surface associated |
| MXRA7 | matrix-remodelling associated 7 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PODXL | podocalyxin-like |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RGS1 | regulator of G-protein signaling 1 |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| S100A8 | S100 calcium binding protein A8 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIX1 | SIX homeobox 1 |
| SLC38A6 | solute carrier family 38, member 6 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM30B | transmembrane protein 30B |
| TMEM47 | transmembrane protein 47 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C1R | complement component 1, r subcomponent |
| CD44 | CD44 molecule (Indian blood group) |
| CD52 | CD52 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| COL10A1 | collagen, type X, alpha 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBXO21 | F-box protein 21 |
| FHL1 | four and a half LIM domains 1 |
| GAL | galanin/GMAP prepropeptide |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GOLGA8A | golgin A8 family, member A |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| MAP7 | microtubule-associated protein 7 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NMU | neuromedin U |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PDLIM5 | PDZ and LIM domain 5 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAT | plasminogen activator, tissue |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PRSS3 | protease, serine, 3 |
| RAB31 | RAB31, member RAS oncogene family |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SFRP4 | secreted frizzled-related protein 4 |
| TLE4 | transducin-like enhancer of split 4 |
| TMX4 | thioredoxin-related transmembrane protein 4 |
| TNC | tenascin C |
| TUFT1 | tuftelin 1 |
| ZNF331 | zinc finger protein 331 |
