| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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193 genes differentially expressed following the BRD-K50234570_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ADM | adrenomedullin |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATF4 | activating transcription factor 4 |
| BTG3 | BTG family, member 3 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CD163 | CD163 molecule |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CENPU | centromere protein U |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLIC4 | chloride intracellular channel 4 |
| COL11A1 | collagen, type XI, alpha 1 |
| CTH | cystathionine gamma-lyase |
| CYB5R1 | cytochrome b5 reductase 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND1B | DENN/MADD domain containing 1B |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP5 | dual specificity phosphatase 5 |
| ECM1 | extracellular matrix protein 1 |
| ELANE | elastase, neutrophil expressed |
| ETV5 | ets variant 5 |
| FAM129A | family with sequence similarity 129, member A |
| FAM69A | family with sequence similarity 69, member A |
| FN1 | fibronectin 1 |
| FOSL1 | FOS-like antigen 1 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GARS | glycyl-tRNA synthetase |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER5 | immediate early response 5 |
| IFRD1 | interferon-related developmental regulator 1 |
| IL1R2 | interleukin 1 receptor, type II |
| INSIG1 | insulin induced gene 1 |
| IPO13 | importin 13 |
| JUN | jun proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MME | membrane metallo-endopeptidase |
| MPO | myeloperoxidase |
| MSLN | mesothelin |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1M | metallothionein 1M |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NIT1 | nitrilase 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSER1 | oxidative stress responsive serine-rich 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PELO | pelota homolog (Drosophila) |
| PLIN2 | perilipin 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSAT1 | phosphoserine aminotransferase 1 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RGCC | regulator of cell cycle |
| RND3 | Rho family GTPase 3 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TES | testin LIM domain protein |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPYL5 | TSPY-like 5 |
| TUBA4A | tubulin, alpha 4a |
| VEGFA | vascular endothelial growth factor A |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ACKR3 | atypical chemokine receptor 3 |
| AGR2 | anterior gradient 2 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 |
| ATF5 | activating transcription factor 5 |
| ATP9A | ATPase, class II, type 9A |
| B3GNT1 | |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BMP2 | bone morphogenetic protein 2 |
| BTBD3 | BTB (POZ) domain containing 3 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CA12 | carbonic anhydrase XII |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD47 | CD47 molecule |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CST3 | cystatin C |
| CTSG | cathepsin G |
| CYBA | cytochrome b-245, alpha polypeptide |
| DAPK1 | death-associated protein kinase 1 |
| DCLK1 | doublecortin-like kinase 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFNB2 | ephrin-B2 |
| EMP3 | epithelial membrane protein 3 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FLNB | filamin B, beta |
| FZD7 | frizzled class receptor 7 |
| GATA3 | GATA binding protein 3 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GOLGA8H | golgin A8 family, member H |
| GOLM1 | golgi membrane protein 1 |
| GPX3 | glutathione peroxidase 3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HES1 | hes family bHLH transcription factor 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HMG20B | high mobility group 20B |
| HOXA5 | homeobox A5 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IFI44L | interferon-induced protein 44-like |
| IGHM | immunoglobulin heavy constant mu |
| IGKC | immunoglobulin kappa constant |
| IGSF3 | immunoglobulin superfamily, member 3 |
| KLK11 | kallikrein-related peptidase 11 |
| KRT16 | keratin 16, type I |
| KRT17 | keratin 17, type I |
| KRT7 | keratin 7, type II |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAGEA3 | melanoma antigen family A3 |
| MARCKSL1 | MARCKS-like 1 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MREG | melanoregulin |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
| NFIB | nuclear factor I/B |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NMB | neuromedin B |
| NNMT | nicotinamide N-methyltransferase |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| POSTN | periostin, osteoblast specific factor |
| PRKCD | protein kinase C, delta |
| PROM1 | prominin 1 |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RBP1 | retinol binding protein 1, cellular |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SACS | sacsin molecular chaperone |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SELL | selectin L |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMAD3 | SMAD family member 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFF1 | trefoil factor 1 |
| TFF3 | trefoil factor 3 (intestinal) |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIM44 | tripartite motif containing 44 |
| TYRP1 | tyrosinase-related protein 1 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| UBL3 | ubiquitin-like 3 |
| VCAN | versican |
| VIM | vimentin |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
