Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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128 genes differentially expressed following the BRD-K50387473_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
BASP1 | brain abundant, membrane attached signal protein 1 |
BRD2 | bromodomain containing 2 |
CA1 | carbonic anhydrase I |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CANX | calnexin |
CCNL1 | cyclin L1 |
CD81 | CD81 molecule |
CES1 | carboxylesterase 1 |
CHGB | chromogranin B |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CREG1 | cellular repressor of E1A-stimulated genes 1 |
CTR9 | CTR9, Paf1/RNA polymerase II complex component |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
FAM117A | family with sequence similarity 117, member A |
FBXO21 | F-box protein 21 |
FLNA | filamin A, alpha |
G6PD | glucose-6-phosphate dehydrogenase |
GALC | galactosylceramidase |
GRN | granulin |
GSDMB | gasdermin B |
GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
H2BFS | H2B histone family, member S (pseudogene) |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HIST1H2BD | histone cluster 1, H2bd |
HIST1H2BF | histone cluster 1, H2bf |
HIST1H2BK | histone cluster 1, H2bk |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IGHM | immunoglobulin heavy constant mu |
L1CAM | L1 cell adhesion molecule |
LEPR | leptin receptor |
MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
MPDZ | multiple PDZ domain protein |
MYO1B | myosin IB |
OPN3 | opsin 3 |
PALLD | palladin, cytoskeletal associated protein |
PKP2 | plakophilin 2 |
RAB4A | RAB4A, member RAS oncogene family |
RBBP6 | retinoblastoma binding protein 6 |
RNF167 | ring finger protein 167 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SCPEP1 | serine carboxypeptidase 1 |
SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
STX1A | syntaxin 1A (brain) |
TGM2 | transglutaminase 2 |
TMED2 | transmembrane emp24 domain trafficking protein 2 |
TRIB2 | tribbles pseudokinase 2 |
TUBA1A | tubulin, alpha 1a |
TUBA4A | tubulin, alpha 4a |
TXNIP | thioredoxin interacting protein |
UBE2S | ubiquitin-conjugating enzyme E2S |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
VIM | vimentin |
YBX1 | Y box binding protein 1 |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
ZFAND5 | zinc finger, AN1-type domain 5 |
Symbol | Name |
---|---|
ABLIM1 | actin binding LIM protein 1 |
AFP | alpha-fetoprotein |
ANXA7 | annexin A7 |
ATF3 | activating transcription factor 3 |
CALB1 | calbindin 1, 28kDa |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
CLDN4 | claudin 4 |
CRIP1 | cysteine-rich protein 1 (intestinal) |
CXCL3 | chemokine (C-X-C motif) ligand 3 |
DRAM1 | DNA-damage regulated autophagy modulator 1 |
DUSP22 | dual specificity phosphatase 22 |
ECM1 | extracellular matrix protein 1 |
EMG1 | EMG1 N1-specific pseudouridine methyltransferase |
EMP1 | epithelial membrane protein 1 |
EVI2A | ecotropic viral integration site 2A |
F5 | coagulation factor V (proaccelerin, labile factor) |
FGFR3 | fibroblast growth factor receptor 3 |
FHL2 | four and a half LIM domains 2 |
GBP1 | guanylate binding protein 1, interferon-inducible |
GLTP | glycolipid transfer protein |
GPR171 | G protein-coupled receptor 171 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HDDC2 | HD domain containing 2 |
HMOX1 | heme oxygenase 1 |
HOPX | HOP homeobox |
HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
ICAM2 | intercellular adhesion molecule 2 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
IL1R2 | interleukin 1 receptor, type II |
KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
KRT23 | keratin 23, type I |
LMO3 | LIM domain only 3 (rhombotin-like 2) |
LOX | lysyl oxidase |
LRRC15 | leucine rich repeat containing 15 |
LYZ | lysozyme |
MSLN | mesothelin |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
PARP2 | poly (ADP-ribose) polymerase 2 |
PCP4 | Purkinje cell protein 4 |
PDGFA | platelet-derived growth factor alpha polypeptide |
PDGFC | platelet derived growth factor C |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PLAC8 | placenta-specific 8 |
PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
PSCA | prostate stem cell antigen |
PSPH | phosphoserine phosphatase |
RAB15 | RAB15, member RAS oncogene family |
RHOBTB3 | Rho-related BTB domain containing 3 |
S100P | S100 calcium binding protein P |
SCEL | sciellin |
SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
SORBS3 | sorbin and SH3 domain containing 3 |
SORD | sorbitol dehydrogenase |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
SPRR1A | small proline-rich protein 1A |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
TF | transferrin |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
TM4SF1 | transmembrane 4 L six family member 1 |
ZMAT3 | zinc finger, matrin-type 3 |