| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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75 genes differentially expressed following the BRD-K51276371_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CFB | complement factor B |
| COL10A1 | collagen, type X, alpha 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| EREG | epiregulin |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNLY | granulysin |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL7R | interleukin 7 receptor |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KRT18 | keratin 18, type I |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| NNMT | nicotinamide N-methyltransferase |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLA2G16 | phospholipase A2, group XVI |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PLS1 | plastin 1 |
| PRKCQ | protein kinase C, theta |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RNF167 | ring finger protein 167 |
| RPIA | ribose 5-phosphate isomerase A |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STX1A | syntaxin 1A (brain) |
| SULF1 | sulfatase 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TRD | T cell receptor delta locus |
| TRDV3 | T cell receptor delta variable 3 |
| TXNDC9 | thioredoxin domain containing 9 |
| VCAN | versican |
| VGLL4 | vestigial-like family member 4 |
| VIM | vimentin |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CA2 | carbonic anhydrase II |
| CDC42 | cell division cycle 42 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CTSZ | cathepsin Z |
| DMD | dystrophin |
| DUSP22 | dual specificity phosphatase 22 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FCGBP | Fc fragment of IgG binding protein |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR3 | fibroblast growth factor receptor 3 |
| HSPA1A | heat shock 70kDa protein 1A |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL6R | interleukin 6 receptor |
| ING2 | inhibitor of growth family, member 2 |
| KLK11 | kallikrein-related peptidase 11 |
| LPL | lipoprotein lipase |
| LY6D | lymphocyte antigen 6 complex, locus D |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PIR | pirin (iron-binding nuclear protein) |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPS11 | ribosomal protein S11 |
| RXRA | retinoid X receptor, alpha |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TMEM100 | transmembrane protein 100 |
| TPM1 | tropomyosin 1 (alpha) |
| TRIM29 | tripartite motif containing 29 |
