Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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70 genes differentially expressed following the BRD-K51276371_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
BSG | basigin (Ok blood group) |
C10ORF10 | chromosome 10 open reading frame 10 |
CD44 | CD44 molecule (Indian blood group) |
COLEC12 | collectin sub-family member 12 |
COPA | coatomer protein complex, subunit alpha |
CXADR | coxsackie virus and adenovirus receptor |
ERBB4 | erb-b2 receptor tyrosine kinase 4 |
F11R | F11 receptor |
HCAR3 | hydroxycarboxylic acid receptor 3 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IL13RA1 | interleukin 13 receptor, alpha 1 |
INHBB | inhibin, beta B |
IQGAP1 | IQ motif containing GTPase activating protein 1 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PEG10 | paternally expressed 10 |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
RND3 | Rho family GTPase 3 |
SDC2 | syndecan 2 |
SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
TUBB2A | tubulin, beta 2A class IIa |
TUBB2B | tubulin, beta 2B class IIb |
TWIST1 | twist family bHLH transcription factor 1 |
WLS | wntless Wnt ligand secretion mediator |
ZNF331 | zinc finger protein 331 |
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADGRG2 | adhesion G protein-coupled receptor G2 |
ADGRG6 | adhesion G protein-coupled receptor G6 |
CKS2 | CDC28 protein kinase regulatory subunit 2 |
CYBA | cytochrome b-245, alpha polypeptide |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
FCGBP | Fc fragment of IgG binding protein |
FOS | FBJ murine osteosarcoma viral oncogene homolog |
FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
GPX2 | glutathione peroxidase 2 |
HAMP | hepcidin antimicrobial peptide |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
IGHM | immunoglobulin heavy constant mu |
INSIG1 | insulin induced gene 1 |
KLF2 | Kruppel-like factor 2 |
LDLR | low density lipoprotein receptor |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
LYZ | lysozyme |
MARCKSL1 | MARCKS-like 1 |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MFAP3L | microfibrillar-associated protein 3-like |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
PHYH | phytanoyl-CoA 2-hydroxylase |
POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
PRKCA | protein kinase C, alpha |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RHOBTB3 | Rho-related BTB domain containing 3 |
RPP25 | ribonuclease P/MRP 25kDa subunit |
RPS27L | ribosomal protein S27-like |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
S100A10 | S100 calcium binding protein A10 |
S100P | S100 calcium binding protein P |
SCAND1 | SCAN domain containing 1 |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |