BRD-K51302260_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K51302260_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
AQP1 aquaporin 1 (Colton blood group)
CA1 carbonic anhydrase I
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
FAM129A family with sequence similarity 129, member A
FTH1 ferritin, heavy polypeptide 1
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
IGFBP4 insulin-like growth factor binding protein 4
LCN2 lipocalin 2
LOX lysyl oxidase
PDZK1IP1 PDZK1 interacting protein 1
PI3 peptidase inhibitor 3, skin-derived
PLAC8 placenta-specific 8
PTX3 pentraxin 3, long
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCD5 stearoyl-CoA desaturase 5
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SRGN serglycin
TFF3 trefoil factor 3 (intestinal)
TTC3 tetratricopeptide repeat domain 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CREB1 cAMP responsive element binding protein 1
FAIM Fas apoptotic inhibitory molecule
FN1 fibronectin 1
IGL immunoglobulin lambda locus
MYO5C myosin VC
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
RBM3 RNA binding motif (RNP1, RRM) protein 3
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SPRED2 sprouty-related, EVH1 domain containing 2
TIMP3 TIMP metallopeptidase inhibitor 3
TPPP3 tubulin polymerization-promoting protein family member 3
UBE2J1 ubiquitin-conjugating enzyme E2, J1
ZW10 zw10 kinetochore protein
Funding