Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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128 genes differentially expressed following the BRD-K51313569_palbociclib_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
ADIRF | adipogenesis regulatory factor |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
ANXA3 | annexin A3 |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
AZU1 | azurocidin 1 |
BEX1 | brain expressed, X-linked 1 |
BST2 | bone marrow stromal cell antigen 2 |
C1ORF106 | chromosome 1 open reading frame 106 |
C1QA | complement component 1, q subcomponent, A chain |
C1QB | complement component 1, q subcomponent, B chain |
CCNG2 | cyclin G2 |
CD36 | CD36 molecule (thrombospondin receptor) |
CD44 | CD44 molecule (Indian blood group) |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CHRDL1 | chordin-like 1 |
CTSG | cathepsin G |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 |
ECHDC2 | enoyl CoA hydratase domain containing 2 |
EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
F13A1 | coagulation factor XIII, A1 polypeptide |
FABP4 | fatty acid binding protein 4, adipocyte |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
HLA-B | major histocompatibility complex, class I, B |
HLA-E | major histocompatibility complex, class I, E |
HLA-G | major histocompatibility complex, class I, G |
IFI27 | interferon, alpha-inducible protein 27 |
IFI44L | interferon-induced protein 44-like |
IRF9 | interferon regulatory factor 9 |
ISG15 | ISG15 ubiquitin-like modifier |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
MFAP5 | microfibrillar associated protein 5 |
MSLN | mesothelin |
MT1E | metallothionein 1E |
MT1X | metallothionein 1X |
MVP | major vault protein |
MX1 | MX dynamin-like GTPase 1 |
NEFH | neurofilament, heavy polypeptide |
NPDC1 | neural proliferation, differentiation and control, 1 |
PALLD | palladin, cytoskeletal associated protein |
PLA2G16 | phospholipase A2, group XVI |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
PRKCI | protein kinase C, iota |
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
SLIT2 | slit homolog 2 (Drosophila) |
SRPX | sushi-repeat containing protein, X-linked |
SST | somatostatin |
TACC2 | transforming, acidic coiled-coil containing protein 2 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TMEM100 | transmembrane protein 100 |
TSPAN8 | tetraspanin 8 |
TTC39A | tetratricopeptide repeat domain 39A |
WFS1 | Wolfram syndrome 1 (wolframin) |
Symbol | Name |
---|---|
ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
AURKA | aurora kinase A |
BIRC5 | baculoviral IAP repeat containing 5 |
CCNA2 | cyclin A2 |
CCNB2 | cyclin B2 |
CCNF | cyclin F |
CDC20 | cell division cycle 20 |
CDC25A | cell division cycle 25A |
CDC25B | cell division cycle 25B |
CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
CDCA3 | cell division cycle associated 3 |
CDK1 | cyclin-dependent kinase 1 |
CDKN3 | cyclin-dependent kinase inhibitor 3 |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CENPA | centromere protein A |
CENPF | centromere protein F, 350/400kDa |
CEP55 | centrosomal protein 55kDa |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
FOXM1 | forkhead box M1 |
FSCN1 | fascin actin-bundling protein 1 |
FXYD5 | FXYD domain containing ion transport regulator 5 |
GLIPR1 | GLI pathogenesis-related 1 |
H2AFV | H2A histone family, member V |
HMGB2 | high mobility group box 2 |
HMGB3 | high mobility group box 3 |
HMMR | hyaluronan-mediated motility receptor (RHAMM) |
HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
KIF20A | kinesin family member 20A |
KRT15 | keratin 15, type I |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LBR | lamin B receptor |
MALL | mal, T-cell differentiation protein-like |
MKI67 | marker of proliferation Ki-67 |
MMP12 | matrix metallopeptidase 12 |
MMP9 | matrix metallopeptidase 9 |
MTSS1 | metastasis suppressor 1 |
MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
MYLK | myosin light chain kinase |
NELL2 | NEL-like 2 (chicken) |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
NRGN | neurogranin (protein kinase C substrate, RC3) |
NUSAP1 | nucleolar and spindle associated protein 1 |
PLK1 | polo-like kinase 1 |
PRC1 | protein regulator of cytokinesis 1 |
PSIP1 | PC4 and SFRS1 interacting protein 1 |
PTTG1 | pituitary tumor-transforming 1 |
RACGAP1 | Rac GTPase activating protein 1 |
RAI14 | retinoic acid induced 14 |
RRAS2 | related RAS viral (r-ras) oncogene homolog 2 |
RUNX3 | runt-related transcription factor 3 |
S100A2 | S100 calcium binding protein A2 |
S100A7 | S100 calcium binding protein A7 |
STMN1 | stathmin 1 |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TNC | tenascin C |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TPX2 | TPX2, microtubule-associated |
TSPYL5 | TSPY-like 5 |
UBE2C | ubiquitin-conjugating enzyme E2C |
UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |