| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
68 genes differentially expressed following the BRD-K51313569_palbociclib_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALDOC | aldolase C, fructose-bisphosphate |
| ARHGAP29 | Rho GTPase activating protein 29 |
| CHGB | chromogranin B |
| DLK1 | delta-like 1 homolog (Drosophila) |
| GPX3 | glutathione peroxidase 3 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GYG2 | glycogenin 2 |
| IFI27 | interferon, alpha-inducible protein 27 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITM2A | integral membrane protein 2A |
| KRT19 | keratin 19, type I |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| MAGED1 | melanoma antigen family D1 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PIR | pirin (iron-binding nuclear protein) |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RNASET2 | ribonuclease T2 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SST | somatostatin |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TSPAN7 | tetraspanin 7 |
| VWF | von Willebrand factor |
| Symbol | Name |
|---|---|
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| CCNA2 | cyclin A2 |
| CCNE2 | cyclin E2 |
| CDCA3 | cell division cycle associated 3 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPA | centromere protein A |
| CENPF | centromere protein F, 350/400kDa |
| CEP55 | centrosomal protein 55kDa |
| ECT2 | epithelial cell transforming 2 |
| EPHA3 | EPH receptor A3 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FANCI | Fanconi anemia, complementation group I |
| FOXM1 | forkhead box M1 |
| HIST1H4C | histone cluster 1, H4c |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HOXA10 | homeobox A10 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIF20A | kinesin family member 20A |
| MELK | maternal embryonic leucine zipper kinase |
| NCAPG2 | non-SMC condensin II complex, subunit G2 |
| NDC80 | NDC80 kinetochore complex component |
| NEK2 | NIMA-related kinase 2 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| PBK | PDZ binding kinase |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| PRR15L | proline rich 15-like |
| RACGAP1 | Rac GTPase activating protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RRM2 | ribonucleotide reductase M2 |
| S100A8 | S100 calcium binding protein A8 |
| SMC2 | structural maintenance of chromosomes 2 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
