Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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108 genes differentially expressed following the BRD-K51575138_TPCA-1_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AARS | alanyl-tRNA synthetase |
ACTA2 | actin, alpha 2, smooth muscle, aorta |
AGR2 | anterior gradient 2 |
AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
APOD | apolipoprotein D |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ASS1 | argininosuccinate synthase 1 |
C1ORF116 | chromosome 1 open reading frame 116 |
C6ORF48 | chromosome 6 open reading frame 48 |
CFD | complement factor D (adipsin) |
COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
CSNK1E | casein kinase 1, epsilon |
DCN | decorin |
DES | desmin |
DUSP1 | dual specificity phosphatase 1 |
EFHD1 | EF-hand domain family, member D1 |
EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
EPRS | glutamyl-prolyl-tRNA synthetase |
ETV5 | ets variant 5 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
IRS2 | insulin receptor substrate 2 |
KRT23 | keratin 23, type I |
LAT2 | linker for activation of T cells family, member 2 |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
LPAR1 | lysophosphatidic acid receptor 1 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
MYBPC1 | myosin binding protein C, slow type |
NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
NREP | neuronal regeneration related protein |
PHGDH | phosphoglycerate dehydrogenase |
PLXND1 | plexin D1 |
PROM1 | prominin 1 |
PRPF4 | pre-mRNA processing factor 4 |
PSAT1 | phosphoserine aminotransferase 1 |
PYCR1 | pyrroline-5-carboxylate reductase 1 |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
S100P | S100 calcium binding protein P |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SORBS2 | sorbin and SH3 domain containing 2 |
STC2 | stanniocalcin 2 |
TARP | TCR gamma alternate reading frame protein |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TNNI2 | troponin I type 2 (skeletal, fast) |
TPM2 | tropomyosin 2 (beta) |
TRIM2 | tripartite motif containing 2 |
TSC22D3 | TSC22 domain family, member 3 |
TSPAN8 | tetraspanin 8 |
WFDC2 | WAP four-disulfide core domain 2 |
ZNF91 | zinc finger protein 91 |
Symbol | Name |
---|---|
ACKR3 | atypical chemokine receptor 3 |
ALDOA | aldolase A, fructose-bisphosphate |
ARL4C | ADP-ribosylation factor-like 4C |
ATAD2 | ATPase family, AAA domain containing 2 |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
AURKB | aurora kinase B |
CALR | calreticulin |
CAV2 | caveolin 2 |
CCL2 | chemokine (C-C motif) ligand 2 |
CD24 | CD24 molecule |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CP | ceruloplasmin (ferroxidase) |
CPA3 | carboxypeptidase A3 (mast cell) |
CPB1 | carboxypeptidase B1 (tissue) |
CRELD2 | cysteine-rich with EGF-like domains 2 |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
EGFR | epidermal growth factor receptor |
ENO1 | enolase 1, (alpha) |
FANCI | Fanconi anemia, complementation group I |
GBP1 | guanylate binding protein 1, interferon-inducible |
GLI2 | GLI family zinc finger 2 |
GOLGA8B | golgin A8 family, member B |
GPNMB | glycoprotein (transmembrane) nmb |
H2AFX | H2A histone family, member X |
HK1 | hexokinase 1 |
IGF1R | insulin-like growth factor 1 receptor |
IGFBP3 | insulin-like growth factor binding protein 3 |
KIF20A | kinesin family member 20A |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
NAV2 | neuron navigator 2 |
PBX3 | pre-B-cell leukemia homeobox 3 |
PCDH7 | protocadherin 7 |
PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
PLAU | plasminogen activator, urokinase |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
PTMA | prothymosin, alpha |
PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
RCN2 | reticulocalbin 2, EF-hand calcium binding domain |
S100A9 | S100 calcium binding protein A9 |
SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
SOCS1 | suppressor of cytokine signaling 1 |
SPRR1B | small proline-rich protein 1B |
TCTN1 | tectonic family member 1 |
TMEM14A | transmembrane protein 14A |
TMEM45A | transmembrane protein 45A |
TNC | tenascin C |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
XIST | X inactive specific transcript (non-protein coding) |
ZFP36L1 | ZFP36 ring finger protein-like 1 |
ZIC1 | Zic family member 1 |