Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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66 genes differentially expressed following the BRD-K51662849_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
CAPN7 | calpain 7 |
CCDC92 | coiled-coil domain containing 92 |
CD58 | CD58 molecule |
CPB1 | carboxypeptidase B1 (tissue) |
DUSP1 | dual specificity phosphatase 1 |
G0S2 | G0/G1 switch 2 |
HBD | hemoglobin, delta |
HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
KDM3A | lysine (K)-specific demethylase 3A |
LDHB | lactate dehydrogenase B |
LOX | lysyl oxidase |
LTF | lactotransferrin |
MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
MTCL1 | microtubule crosslinking factor 1 |
MYO6 | myosin VI |
NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
NOX4 | NADPH oxidase 4 |
NRN1 | neuritin 1 |
NUP98 | nucleoporin 98kDa |
PDLIM5 | PDZ and LIM domain 5 |
PERP | PERP, TP53 apoptosis effector |
PIGB | phosphatidylinositol glycan anchor biosynthesis, class B |
POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
PRAME | preferentially expressed antigen in melanoma |
RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TPD52L2 | tumor protein D52-like 2 |
TRBC1 | T cell receptor beta constant 1 |
TXNIP | thioredoxin interacting protein |
VAV3 | vav 3 guanine nucleotide exchange factor |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
Symbol | Name |
---|---|
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
ATF3 | activating transcription factor 3 |
CCND1 | cyclin D1 |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
EIF4A1 | eukaryotic translation initiation factor 4A1 |
EIF5 | eukaryotic translation initiation factor 5 |
FCGBP | Fc fragment of IgG binding protein |
FLNA | filamin A, alpha |
GPM6B | glycoprotein M6B |
IGF1 | insulin-like growth factor 1 (somatomedin C) |
IGHD | immunoglobulin heavy constant delta |
ISLR | immunoglobulin superfamily containing leucine-rich repeat |
LDLR | low density lipoprotein receptor |
LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
NFATC2IP | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
PAPD7 | PAP associated domain containing 7 |
PEG10 | paternally expressed 10 |
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
RNF167 | ring finger protein 167 |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
SNX7 | sorting nexin 7 |
SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
STAB1 | stabilin 1 |
SYBU | syntabulin (syntaxin-interacting) |
TPBG | trophoblast glycoprotein |