Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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96 genes differentially expressed following the BRD-K51781482_IKK-3 Inhibitor IX_SW620_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
BPHL | biphenyl hydrolase-like (serine hydrolase) |
CA2 | carbonic anhydrase II |
CALR | calreticulin |
CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
CAST | calpastatin |
CD58 | CD58 molecule |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHN1 | chimerin 1 |
CSTA | cystatin A (stefin A) |
CXADR | coxsackie virus and adenovirus receptor |
CYCS | cytochrome c, somatic |
DCLK1 | doublecortin-like kinase 1 |
DLD | dihydrolipoamide dehydrogenase |
DLK1 | delta-like 1 homolog (Drosophila) |
DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
DST | dystonin |
ENO1 | enolase 1, (alpha) |
F11R | F11 receptor |
FSCN1 | fascin actin-bundling protein 1 |
G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
GRB7 | growth factor receptor-bound protein 7 |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
IL17RB | interleukin 17 receptor B |
JAG1 | jagged 1 |
KLF11 | Kruppel-like factor 11 |
KRT17 | keratin 17, type I |
KRT6A | keratin 6A, type II |
KRT7 | keratin 7, type II |
KRT81 | keratin 81, type II |
KYNU | kynureninase |
LMO3 | LIM domain only 3 (rhombotin-like 2) |
MTSS1 | metastasis suppressor 1 |
MYBPC1 | myosin binding protein C, slow type |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
OLFM1 | olfactomedin 1 |
PDE4B | phosphodiesterase 4B, cAMP-specific |
PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
PKM | pyruvate kinase, muscle |
PODXL | podocalyxin-like |
PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
PSD3 | pleckstrin and Sec7 domain containing 3 |
PTN | pleiotrophin |
RAPGEF4 | Rap guanine nucleotide exchange factor (GEF) 4 |
RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
SDC1 | syndecan 1 |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SIK1 | salt-inducible kinase 1 |
TRIM2 | tripartite motif containing 2 |
TUBB2A | tubulin, beta 2A class IIa |
VNN1 | vanin 1 |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
Symbol | Name |
---|---|
AGR2 | anterior gradient 2 |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
ASMTL | acetylserotonin O-methyltransferase-like |
AXIN1 | axin 1 |
BEX1 | brain expressed, X-linked 1 |
CD99 | CD99 molecule |
CES1 | carboxylesterase 1 |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
CYTL1 | cytokine-like 1 |
DCXR | dicarbonyl/L-xylulose reductase |
DDHD2 | DDHD domain containing 2 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FZD2 | frizzled class receptor 2 |
GPX3 | glutathione peroxidase 3 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IL1R2 | interleukin 1 receptor, type II |
INHBA | inhibin, beta A |
KDM5D | lysine (K)-specific demethylase 5D |
KLK11 | kallikrein-related peptidase 11 |
LAMP5 | lysosomal-associated membrane protein family, member 5 |
LTBP3 | latent transforming growth factor beta binding protein 3 |
MXRA7 | matrix-remodelling associated 7 |
MYB | v-myb avian myeloblastosis viral oncogene homolog |
NEFH | neurofilament, heavy polypeptide |
NKG7 | natural killer cell granule protein 7 |
NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
OLFM4 | olfactomedin 4 |
PAAF1 | proteasomal ATPase-associated factor 1 |
PENK | proenkephalin |
RELN | reelin |
SIDT2 | SID1 transmembrane family, member 2 |
SLC46A3 | solute carrier family 46, member 3 |
TBL1X | transducin (beta)-like 1X-linked |
ZNF586 | zinc finger protein 586 |