BRD-K51918615_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K51918615_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKRD10 ankyrin repeat domain 10
ANXA3 annexin A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BCL6 B-cell CLL/lymphoma 6
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCNG2 cyclin G2
CDKN2A cyclin-dependent kinase inhibitor 2A
COCH cochlin
DDIT4 DNA-damage-inducible transcript 4
DESI2 desumoylating isopeptidase 2
DHCR24 24-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
FADS1 fatty acid desaturase 1
FAM129A family with sequence similarity 129, member A
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INSIG1 insulin induced gene 1
KIAA0907 KIAA0907
LDLR low density lipoprotein receptor
LPIN2 lipin 2
MAP2K3 mitogen-activated protein kinase kinase 3
MSMO1 methylsterol monooxygenase 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
OSBPL10 oxysterol binding protein-like 10
PDGFC platelet derived growth factor C
RBP1 retinol binding protein 1, cellular
SIAH2 siah E3 ubiquitin protein ligase 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMAD3 SMAD family member 3
STK17A serine/threonine kinase 17a
TACSTD2 tumor-associated calcium signal transducer 2
TM4SF1 transmembrane 4 L six family member 1
WEE1 WEE1 G2 checkpoint kinase
ZEB2 zinc finger E-box binding homeobox 2
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
CCDC85B coiled-coil domain containing 85B
CD14 CD14 molecule
CD93 CD93 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNPY3 canopy FGF signaling regulator 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FCGBP Fc fragment of IgG binding protein
FLNB filamin B, beta
HIST1H4C histone cluster 1, H4c
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
MAP7 microtubule-associated protein 7
MGP matrix Gla protein
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEG3 paternally expressed 3
PODXL podocalyxin-like
POSTN periostin, osteoblast specific factor
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SRSF7 serine/arginine-rich splicing factor 7
Funding