Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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72 genes differentially expressed following the BRD-K51998148_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
BEX1 | brain expressed, X-linked 1 |
BHLHE40 | basic helix-loop-helix family, member e40 |
CA2 | carbonic anhydrase II |
CCDC86 | coiled-coil domain containing 86 |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CLIC4 | chloride intracellular channel 4 |
CTSH | cathepsin H |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL13 | chemokine (C-X-C motif) ligand 13 |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DAPK1 | death-associated protein kinase 1 |
DCN | decorin |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
FADS1 | fatty acid desaturase 1 |
GNAS | GNAS complex locus |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IL32 | interleukin 32 |
KRT17 | keratin 17, type I |
LAT2 | linker for activation of T cells family, member 2 |
MAP7 | microtubule-associated protein 7 |
MN1 | meningioma (disrupted in balanced translocation) 1 |
PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
PHACTR2 | phosphatase and actin regulator 2 |
PLCB4 | phospholipase C, beta 4 |
RGS5 | regulator of G-protein signaling 5 |
SPRR1A | small proline-rich protein 1A |
STK26 | serine/threonine protein kinase 26 |
TCF4 | transcription factor 4 |
TSPAN13 | tetraspanin 13 |
WIF1 | WNT inhibitory factor 1 |
Symbol | Name |
---|---|
ALOX5 | arachidonate 5-lipoxygenase |
ARL4A | ADP-ribosylation factor-like 4A |
CALB1 | calbindin 1, 28kDa |
CAST | calpastatin |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CCNE2 | cyclin E2 |
CNN1 | calponin 1, basic, smooth muscle |
COL1A2 | collagen, type I, alpha 2 |
CRISP3 | cysteine-rich secretory protein 3 |
CXCL5 | chemokine (C-X-C motif) ligand 5 |
CXCL6 | chemokine (C-X-C motif) ligand 6 |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
EMP1 | epithelial membrane protein 1 |
EVI2A | ecotropic viral integration site 2A |
EVI2B | ecotropic viral integration site 2B |
FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
GPM6B | glycoprotein M6B |
HIST1H2AC | histone cluster 1, H2ac |
IGFBP5 | insulin-like growth factor binding protein 5 |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
KLK10 | kallikrein-related peptidase 10 |
KLK11 | kallikrein-related peptidase 11 |
LCN2 | lipocalin 2 |
LEPR | leptin receptor |
LMO4 | LIM domain only 4 |
LPL | lipoprotein lipase |
PEG10 | paternally expressed 10 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PRUNE2 | prune homolog 2 (Drosophila) |
PTX3 | pentraxin 3, long |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SET | SET nuclear proto-oncogene |
SH3YL1 | SH3 and SYLF domain containing 1 |
SPEN | spen family transcriptional repressor |
SRPX | sushi-repeat containing protein, X-linked |
SRSF7 | serine/arginine-rich splicing factor 7 |
VAT1 | vesicle amine transport 1 |