| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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191 genes differentially expressed following the BRD-K52163391_NCGC00165208-01_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACKR3 | atypical chemokine receptor 3 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALB | albumin |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOC3 | apolipoprotein C-III |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| CADM1 | cell adhesion molecule 1 |
| CCND2 | cyclin D2 |
| CD9 | CD9 molecule |
| CDO1 | cysteine dioxygenase type 1 |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| CLCA1 | chloride channel accessory 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| COMP | cartilage oligomeric matrix protein |
| CTH | cystathionine gamma-lyase |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DACH1 | dachshund family transcription factor 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DEFA6 | defensin, alpha 6, Paneth cell-specific |
| DICER1 | dicer 1, ribonuclease type III |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DPEP1 | dipeptidase 1 (renal) |
| ELMO1 | engulfment and cell motility 1 |
| EPHB2 | EPH receptor B2 |
| FABP1 | fatty acid binding protein 1, liver |
| FAM117A | family with sequence similarity 117, member A |
| FTH1 | ferritin, heavy polypeptide 1 |
| FZD5 | frizzled class receptor 5 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GPX2 | glutathione peroxidase 2 |
| HBD | hemoglobin, delta |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST2H2BE | histone cluster 2, H2be |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITM2C | integral membrane protein 2C |
| JAG1 | jagged 1 |
| KLHL9 | kelch-like family member 9 |
| KRT20 | keratin 20, type I |
| LEFTY1 | left-right determination factor 1 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MMD | monocyte to macrophage differentiation-associated |
| MMP10 | matrix metallopeptidase 10 |
| MMP12 | matrix metallopeptidase 12 |
| MMP3 | matrix metallopeptidase 3 |
| MTSS1 | metastasis suppressor 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NOX1 | NADPH oxidase 1 |
| NPTX2 | neuronal pentraxin II |
| NRCAM | neuronal cell adhesion molecule |
| OLFM4 | olfactomedin 4 |
| ORC1 | origin recognition complex, subunit 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RAP2A | RAP2A, member of RAS oncogene family |
| RBP1 | retinol binding protein 1, cellular |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| REG1B | regenerating islet-derived 1 beta |
| REG3A | regenerating islet-derived 3 alpha |
| RGS13 | regulator of G-protein signaling 13 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCG5 | secretogranin V |
| SNAI2 | snail family zinc finger 2 |
| SRGN | serglycin |
| SST | somatostatin |
| SYT1 | synaptotagmin I |
| TGFB2 | transforming growth factor, beta 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TRAF5 | TNF receptor-associated factor 5 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN12 | tetraspanin 12 |
| TXNRD1 | thioredoxin reductase 1 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ACAT1 | acetyl-CoA acetyltransferase 1 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADCY1 | adenylate cyclase 1 (brain) |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANXA3 | annexin A3 |
| APOD | apolipoprotein D |
| ATAD2 | ATPase family, AAA domain containing 2 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CCNA2 | cyclin A2 |
| CCND1 | cyclin D1 |
| CD59 | CD59 molecule, complement regulatory protein |
| CD81 | CD81 molecule |
| CDC45 | cell division cycle 45 |
| CHPT1 | choline phosphotransferase 1 |
| COCH | cochlin |
| CRYAB | crystallin, alpha B |
| CTSD | cathepsin D |
| CTTN | cortactin |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DCK | deoxycytidine kinase |
| DEFB1 | defensin, beta 1 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EIF4B | eukaryotic translation initiation factor 4B |
| FGF13 | fibroblast growth factor 13 |
| FHL2 | four and a half LIM domains 2 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| HOXC6 | homeobox C6 |
| ICAM3 | intercellular adhesion molecule 3 |
| IER3 | immediate early response 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| JADE2 | jade family PHD finger 2 |
| KIAA0101 | KIAA0101 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT17 | keratin 17, type I |
| KRT6B | keratin 6B, type II |
| LDLR | low density lipoprotein receptor |
| LMNB1 | lamin B1 |
| LTF | lactotransferrin |
| MCM5 | minichromosome maintenance complex component 5 |
| MLPH | melanophilin |
| MUC1 | mucin 1, cell surface associated |
| MYBPC1 | myosin binding protein C, slow type |
| NFIB | nuclear factor I/B |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NOV | nephroblastoma overexpressed |
| OSBPL1A | oxysterol binding protein-like 1A |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PBK | PDZ binding kinase |
| PKP1 | plakophilin 1 |
| PLAC8 | placenta-specific 8 |
| PLIN1 | perilipin 1 |
| PLK1 | polo-like kinase 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POSTN | periostin, osteoblast specific factor |
| PPIF | peptidylprolyl isomerase F |
| PRC1 | protein regulator of cytokinesis 1 |
| PROM1 | prominin 1 |
| PRSS23 | protease, serine, 23 |
| RCAN1 | regulator of calcineurin 1 |
| RPS11 | ribosomal protein S11 |
| RRM1 | ribonucleotide reductase M1 |
| SFN | stratifin |
| SFRP1 | secreted frizzled-related protein 1 |
| SFTPA2 | surfactant protein A2 |
| SFTPB | surfactant protein B |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SLC2A4RG | SLC2A4 regulator |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STMN1 | stathmin 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TLK2 | tousled-like kinase 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TSPAN4 | tetraspanin 4 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| XBP1 | X-box binding protein 1 |
| ZNF512B | zinc finger protein 512B |
