BRD-K52560704_methylstat_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K52560704_methylstat_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
ANPEP alanyl (membrane) aminopeptidase
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BPIFA1 BPI fold containing family A, member 1
BTG1 B-cell translocation gene 1, anti-proliferative
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CCNA1 cyclin A1
CD9 CD9 molecule
CHN1 chimerin 1
CPA3 carboxypeptidase A3 (mast cell)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
EPS8 epidermal growth factor receptor pathway substrate 8
FAM13A family with sequence similarity 13, member A
FGFR1 fibroblast growth factor receptor 1
FOXG1 forkhead box G1
FSCN1 fascin actin-bundling protein 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
HPRT1 hypoxanthine phosphoribosyltransferase 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IPO13 importin 13
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD12 potassium channel tetramerization domain containing 12
MBNL2 muscleblind-like splicing regulator 2
MMP10 matrix metallopeptidase 10
MSMB microseminoprotein, beta-
MUC16 mucin 16, cell surface associated
NKX3-1 NK3 homeobox 1
PEG10 paternally expressed 10
PLIN2 perilipin 2
PPAP2B phosphatidic acid phosphatase type 2B
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PXMP2 peroxisomal membrane protein 2, 22kDa
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGCC regulator of cell cycle
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB2A2 secretoglobin, family 2A, member 2
SDC1 syndecan 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPDEF SAM pointed domain containing ETS transcription factor
SPON2 spondin 2, extracellular matrix protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TM9SF3 transmembrane 9 superfamily member 3
YBX3 Y box binding protein 3

decreased expression

Symbol Name
ANXA3 annexin A3
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CD24 CD24 molecule
CD47 CD47 molecule
CPVL carboxypeptidase, vitellogenic-like
DARS aspartyl-tRNA synthetase
FAM162A family with sequence similarity 162, member A
GRB14 growth factor receptor-bound protein 14
IFT57 intraflagellar transport 57
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6 interleukin 6
LCN2 lipocalin 2
MGP matrix Gla protein
MOK MOK protein kinase
NRCAM neuronal cell adhesion molecule
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
QPCT glutaminyl-peptide cyclotransferase
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RRM2 ribonucleotide reductase M2
SORBS3 sorbin and SH3 domain containing 3
TBX2 T-box 2
TRIB3 tribbles pseudokinase 3
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
Funding