BRD-K52800308_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K52800308_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM9 ADAM metallopeptidase domain 9
ADAMDEC1 ADAM-like, decysin 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CD52 CD52 molecule
CD9 CD9 molecule
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLIC4 chloride intracellular channel 4
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A2 collagen, type I, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CXCL9 chemokine (C-X-C motif) ligand 9
CYBB cytochrome b-245, beta polypeptide
DCN decorin
DEGS1 delta(4)-desaturase, sphingolipid 1
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPAS1 endothelial PAS domain protein 1
EXPH5 exophilin 5
FILIP1L filamin A interacting protein 1-like
FZD5 frizzled class receptor 5
GCLC glutamate-cysteine ligase, catalytic subunit
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
HMOX1 heme oxygenase 1
IL1R1 interleukin 1 receptor, type I
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
MME membrane metallo-endopeptidase
MMP9 matrix metallopeptidase 9
MYH11 myosin, heavy chain 11, smooth muscle
NOX4 NADPH oxidase 4
NUPR1 nuclear protein, transcriptional regulator, 1
OLFM4 olfactomedin 4
PPAP2B phosphatidic acid phosphatase type 2B
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRO protein tyrosine phosphatase, receptor type, O
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A8 S100 calcium binding protein A8
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SNX13 sorting nexin 13
STS steroid sulfatase (microsomal), isozyme S
SULF1 sulfatase 1
TARP TCR gamma alternate reading frame protein
TPD52L1 tumor protein D52-like 1
TPSAB1 tryptase alpha/beta 1
TRIM2 tripartite motif containing 2
TXNRD1 thioredoxin reductase 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
WFDC1 WAP four-disulfide core domain 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ANXA5 annexin A5
ARFIP2 ADP-ribosylation factor interacting protein 2
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
CDA cytidine deaminase
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
DEFB1 defensin, beta 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FKBP11 FK506 binding protein 11, 19 kDa
FLNB filamin B, beta
GNAS GNAS complex locus
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP4 insulin-like growth factor binding protein 4
IL1R2 interleukin 1 receptor, type II
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KRT10 keratin 10, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LIG1 ligase I, DNA, ATP-dependent
MRPS16 mitochondrial ribosomal protein S16
MSLN mesothelin
MX2 MX dynamin-like GTPase 2
PGAM1 phosphoglycerate mutase 1 (brain)
PRSS3 protease, serine, 3
PSPH phosphoserine phosphatase
RPN2 ribophorin II
S100A2 S100 calcium binding protein A2
SPTBN1 spectrin, beta, non-erythrocytic 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNIP1 TNFAIP3 interacting protein 1
TSPAN3 tetraspanin 3
TUBB tubulin, beta class I
UBE2A ubiquitin-conjugating enzyme E2A