| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
110 genes differentially expressed following the BRD-K52850071_JAK3 Inhibitor II_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| ACOT13 | acyl-CoA thioesterase 13 |
| AIM2 | absent in melanoma 2 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPN | asporin |
| BCL6 | B-cell CLL/lymphoma 6 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1QB | complement component 1, q subcomponent, B chain |
| CA2 | carbonic anhydrase II |
| CAT | catalase |
| CBS | cystathionine-beta-synthase |
| CD14 | CD14 molecule |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CPA3 | carboxypeptidase A3 (mast cell) |
| ECI1 | enoyl-CoA delta isomerase 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| FBN2 | fibrillin 2 |
| FLOT1 | flotillin 1 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GLUL | glutamate-ammonia ligase |
| GUSB | glucuronidase, beta |
| GUSBP11 | glucuronidase, beta pseudogene 11 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGHM | immunoglobulin heavy constant mu |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| MAOA | monoamine oxidase A |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MARS | methionyl-tRNA synthetase |
| MEX3D | mex-3 RNA binding family member D |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NGRN | neugrin, neurite outgrowth associated |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NVL | nuclear VCP-like |
| PHGDH | phosphoglycerate dehydrogenase |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) |
| RGCC | regulator of cell cycle |
| RGS2 | regulator of G-protein signaling 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| TPD52L1 | tumor protein D52-like 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WARS | tryptophanyl-tRNA synthetase |
| Symbol | Name |
|---|---|
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANXA5 | annexin A5 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| CBFB | core-binding factor, beta subunit |
| CBR3 | carbonyl reductase 3 |
| CCND1 | cyclin D1 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CHL1 | cell adhesion molecule L1-like |
| CLDN10 | claudin 10 |
| COL1A1 | collagen, type I, alpha 1 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYCS | cytochrome c, somatic |
| DEFB1 | defensin, beta 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLK1 | delta-like 1 homolog (Drosophila) |
| EBP | emopamil binding protein (sterol isomerase) |
| EGR3 | early growth response 3 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM98A | family with sequence similarity 98, member A |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GLIPR1 | GLI pathogenesis-related 1 |
| HN1 | hematological and neurological expressed 1 |
| HOMER1 | homer scaffolding protein 1 |
| HSPA8 | heat shock 70kDa protein 8 |
| IL6ST | interleukin 6 signal transducer |
| KRT10 | keratin 10, type I |
| MOK | MOK protein kinase |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| PDLIM4 | PDZ and LIM domain 4 |
| PON2 | paraoxonase 2 |
| PPIF | peptidylprolyl isomerase F |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGES | prostaglandin E synthase |
| PTMA | prothymosin, alpha |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RPL27A | ribosomal protein L27a |
| RPL37A | ribosomal protein L37a |
| RPL38 | ribosomal protein L38 |
| RPS11 | ribosomal protein S11 |
| S100A2 | S100 calcium binding protein A2 |
| SFN | stratifin |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SRPRB | signal recognition particle receptor, B subunit |
| SRPX | sushi-repeat containing protein, X-linked |
| STOM | stomatin |
| TMF1 | TATA element modulatory factor 1 |
| TSPAN8 | tetraspanin 8 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
