| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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80 genes differentially expressed following the BRD-K52850071_JAK3 Inhibitor II_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| BEX1 | brain expressed, X-linked 1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CA2 | carbonic anhydrase II |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| COL4A5 | collagen, type IV, alpha 5 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
| FRY | furry homolog (Drosophila) |
| GALC | galactosylceramidase |
| GUSBP11 | glucuronidase, beta pseudogene 11 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGHD | immunoglobulin heavy constant delta |
| IGHM | immunoglobulin heavy constant mu |
| IGL | immunoglobulin lambda locus |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| PHGDH | phosphoglycerate dehydrogenase |
| PYCARD | PYD and CARD domain containing |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RTN1 | reticulon 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SFTPB | surfactant protein B |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TFF3 | trefoil factor 3 (intestinal) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRD | T cell receptor delta locus |
| TRDV3 | T cell receptor delta variable 3 |
| TRIB3 | tribbles pseudokinase 3 |
| TXNIP | thioredoxin interacting protein |
| WARS | tryptophanyl-tRNA synthetase |
| Symbol | Name |
|---|---|
| ATF3 | activating transcription factor 3 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| BAG2 | BCL2-associated athanogene 2 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| BCL2A1 | BCL2-related protein A1 |
| CCNG1 | cyclin G1 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CENPN | centromere protein N |
| CHEK1 | checkpoint kinase 1 |
| CHPT1 | choline phosphotransferase 1 |
| CRISP3 | cysteine-rich secretory protein 3 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CYCS | cytochrome c, somatic |
| DARS | aspartyl-tRNA synthetase |
| EIF4B | eukaryotic translation initiation factor 4B |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| HOMER1 | homer scaffolding protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| LAMC2 | laminin, gamma 2 |
| LYPLA1 | lysophospholipase I |
| MREG | melanoregulin |
| MXRA7 | matrix-remodelling associated 7 |
| NCK2 | NCK adaptor protein 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| PEBP1 | phosphatidylethanolamine binding protein 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| RRAGD | Ras-related GTP binding D |
| SAMD4A | sterile alpha motif domain containing 4A |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TYRP1 | tyrosinase-related protein 1 |
| XPO7 | exportin 7 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
