BRD-K52850071_JAK3 Inhibitor II_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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36 genes differentially expressed following the BRD-K52850071_JAK3 Inhibitor II_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CEMIP cell migration inducing protein, hyaluronan binding
CTSB cathepsin B
GABARAPL1 GABA(A) receptor-associated protein like 1
GLRX glutaredoxin (thioltransferase)
HIST1H1C histone cluster 1, H1c
HOXB2 homeobox B2
LGALS8 lectin, galactoside-binding, soluble, 8
NEB nebulin
NNMT nicotinamide N-methyltransferase
NR1H2 nuclear receptor subfamily 1, group H, member 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RBPMS RNA binding protein with multiple splicing
RNH1 ribonuclease/angiogenin inhibitor 1
SH3GL3 SH3-domain GRB2-like 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
VLDLR very low density lipoprotein receptor

decreased expression

Symbol Name
CBR3 carbonyl reductase 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CYTL1 cytokine-like 1
EIF5A eukaryotic translation initiation factor 5A
G0S2 G0/G1 switch 2
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
IDI1 isopentenyl-diphosphate delta isomerase 1
NFIB nuclear factor I/B
PCDH9 protocadherin 9
PPIF peptidylprolyl isomerase F
PRR7 proline rich 7 (synaptic)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SRPX sushi-repeat containing protein, X-linked
TMEM97 transmembrane protein 97
TP53 tumor protein p53