BRD-K52911425_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K52911425_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL10A1 collagen, type X, alpha 1
COMP cartilage oligomeric matrix protein
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF4B eukaryotic translation initiation factor 4B
FADS1 fatty acid desaturase 1
H1F0 H1 histone family, member 0
KDM5D lysine (K)-specific demethylase 5D
KLHDC2 kelch domain containing 2
LRRC15 leucine rich repeat containing 15
MAPT microtubule-associated protein tau
MVP major vault protein
PLAU plasminogen activator, urokinase
PNKP polynucleotide kinase 3'-phosphatase
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RPL37A ribosomal protein L37a
SCCPDH saccharopine dehydrogenase (putative)
TP53 tumor protein p53
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ARF4 ADP-ribosylation factor 4
CDC25A cell division cycle 25A
COBLL1 cordon-bleu WH2 repeat protein-like 1
CSRP2 cysteine and glycine-rich protein 2
DDIT4 DNA-damage-inducible transcript 4
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM69A family with sequence similarity 69, member A
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GSTA1 glutathione S-transferase alpha 1
HAT1 histone acetyltransferase 1
HSPA1A heat shock 70kDa protein 1A
JMJD6 jumonji domain containing 6
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NID1 nidogen 1
NT5DC2 5'-nucleotidase domain containing 2
PDGFC platelet derived growth factor C
PER3 period circadian clock 3
PODXL podocalyxin-like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBX1 ring-box 1, E3 ubiquitin protein ligase
RHOBTB3 Rho-related BTB domain containing 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SDC2 syndecan 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TACSTD2 tumor-associated calcium signal transducer 2
WNT5A wingless-type MMTV integration site family, member 5A