| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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260 genes differentially expressed following the BRD-K52911425_GDC-0941_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ABHD4 | abhydrolase domain containing 4 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ATG14 | autophagy related 14 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BCL6 | B-cell CLL/lymphoma 6 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1RL | complement component 1, r subcomponent-like |
| CA11 | carbonic anhydrase XI |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCDC28A | coiled-coil domain containing 28A |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDK19 | cyclin-dependent kinase 19 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CERK | ceramide kinase |
| CFB | complement factor B |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CP | ceruloplasmin (ferroxidase) |
| CPVL | carboxypeptidase, vitellogenic-like |
| CREBL2 | cAMP responsive element binding protein-like 2 |
| CTSH | cathepsin H |
| CTSV | cathepsin V |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| CYTH1 | cytohesin 1 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EFNA1 | ephrin-A1 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| ETHE1 | ethylmalonic encephalopathy 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FOXO4 | forkhead box O4 |
| GAA | glucosidase, alpha; acid |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLUL | glutamate-ammonia ligase |
| GRN | granulin |
| H1F0 | H1 histone family, member 0 |
| HBP1 | HMG-box transcription factor 1 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HECA | headcase homolog (Drosophila) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST2H2BE | histone cluster 2, H2be |
| HMOX1 | heme oxygenase 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| INSR | insulin receptor |
| KDM3A | lysine (K)-specific demethylase 3A |
| KIAA0430 | KIAA0430 |
| KLHDC2 | kelch domain containing 2 |
| KLHL24 | kelch-like family member 24 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MVP | major vault protein |
| MXI1 | MAX interactor 1, dimerization protein |
| MYLIP | myosin regulatory light chain interacting protein |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAV2 | neuron navigator 2 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NOS3 | nitric oxide synthase 3 (endothelial cell) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PYCARD | PYD and CARD domain containing |
| RAB13 | RAB13, member RAS oncogene family |
| RAB31 | RAB31, member RAS oncogene family |
| RAB5B | RAB5B, member RAS oncogene family |
| RABAC1 | Rab acceptor 1 (prenylated) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RBM47 | RNA binding motif protein 47 |
| RGCC | regulator of cell cycle |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RNF103 | ring finger protein 103 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RSRP1 | arginine/serine-rich protein 1 |
| RTN2 | reticulon 2 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SECISBP2L | SECIS binding protein 2-like |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERINC1 | serine incorporator 1 |
| SERINC3 | serine incorporator 3 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SNX1 | sorting nexin 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SQSTM1 | sequestosome 1 |
| STAB1 | stabilin 1 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| STOM | stomatin |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| TMEM50A | transmembrane protein 50A |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNS3 | tensin 3 |
| TPP1 | tripeptidyl peptidase I |
| TRAK2 | trafficking protein, kinesin binding 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AK4 | adenylate kinase 4 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATF5 | activating transcription factor 5 |
| BOP1 | block of proliferation 1 |
| BZW2 | basic leucine zipper and W2 domains 2 |
| C1QBP | complement component 1, q subcomponent binding protein |
| CCND1 | cyclin D1 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDK4 | cyclin-dependent kinase 4 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CENPN | centromere protein N |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL5A1 | collagen, type V, alpha 1 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CTPS1 | CTP synthase 1 |
| CYCS | cytochrome c, somatic |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DBF4 | DBF4 zinc finger |
| DHCR7 | 7-dehydrocholesterol reductase |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ELOVL1 | ELOVL fatty acid elongase 1 |
| ENO1 | enolase 1, (alpha) |
| EXO1 | exonuclease 1 |
| EXOSC2 | exosome component 2 |
| EXOSC8 | exosome component 8 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM57A | family with sequence similarity 57, member A |
| FEN1 | flap structure-specific endonuclease 1 |
| FOSL1 | FOS-like antigen 1 |
| G0S2 | G0/G1 switch 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAL | galanin/GMAP prepropeptide |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| HN1 | hematological and neurological expressed 1 |
| HOXC6 | homeobox C6 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IGHD | immunoglobulin heavy constant delta |
| IPO5 | importin 5 |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| LMNB1 | lamin B1 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAP1B | microtubule-associated protein 1B |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM6 | minichromosome maintenance complex component 6 |
| MCM7 | minichromosome maintenance complex component 7 |
| MELK | maternal embryonic leucine zipper kinase |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MINA | MYC induced nuclear antigen |
| MMP12 | matrix metallopeptidase 12 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MTCH2 | mitochondrial carrier 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NAV3 | neuron navigator 3 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NOP16 | NOP16 nucleolar protein |
| NRG1 | neuregulin 1 |
| NUP155 | nucleoporin 155kDa |
| NUP88 | nucleoporin 88kDa |
| ODC1 | ornithine decarboxylase 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PCDH9 | protocadherin 9 |
| PFKP | phosphofructokinase, platelet |
| PNP | purine nucleoside phosphorylase |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPIF | peptidylprolyl isomerase F |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
| RAD51 | RAD51 recombinase |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RANBP1 | RAN binding protein 1 |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM2 | ribonucleotide reductase M2 |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SFN | stratifin |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC43A3 | solute carrier family 43, member 3 |
| SPRR1A | small proline-rich protein 1A |
| SPRR3 | small proline-rich protein 3 |
| SRM | spermidine synthase |
| SRPRB | signal recognition particle receptor, B subunit |
| STIP1 | stress-induced phosphoprotein 1 |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TCP1 | t-complex 1 |
| TGFA | transforming growth factor, alpha |
| TIPIN | TIMELESS interacting protein |
| TMEM97 | transmembrane protein 97 |
| TPM1 | tropomyosin 1 (alpha) |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB3 | tubulin, beta 3 class III |
| TUBG1 | tubulin, gamma 1 |
| TYMS | thymidylate synthetase |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| VRK1 | vaccinia related kinase 1 |
| WDR43 | WD repeat domain 43 |
| WSB2 | WD repeat and SOCS box containing 2 |
