Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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104 genes differentially expressed following the BRD-K52911425_GDC-0941_HA1E_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
AMOTL2 | angiomotin like 2 |
ARID5B | AT rich interactive domain 5B (MRF1-like) |
BAMBI | BMP and activin membrane-bound inhibitor |
C10ORF10 | chromosome 10 open reading frame 10 |
CBR3 | carbonyl reductase 3 |
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
COL5A2 | collagen, type V, alpha 2 |
CREBL2 | cAMP responsive element binding protein-like 2 |
CSRP2 | cysteine and glycine-rich protein 2 |
DHFR | dihydrofolate reductase |
DPYD | dihydropyrimidine dehydrogenase |
DUSP6 | dual specificity phosphatase 6 |
E2F2 | E2F transcription factor 2 |
ECM1 | extracellular matrix protein 1 |
EDN1 | endothelin 1 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
FOXG1 | forkhead box G1 |
GREM1 | gremlin 1, DAN family BMP antagonist |
HIST1H4C | histone cluster 1, H4c |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
IFI16 | interferon, gamma-inducible protein 16 |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
IGLL1 | immunoglobulin lambda-like polypeptide 1 |
IRS2 | insulin receptor substrate 2 |
ITGB5 | integrin, beta 5 |
KLHL2 | kelch-like family member 2 |
KRAS | Kirsten rat sarcoma viral oncogene homolog |
LIMCH1 | LIM and calponin homology domains 1 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MBP | myelin basic protein |
MMP1 | matrix metallopeptidase 1 |
MTCL1 | microtubule crosslinking factor 1 |
NREP | neuronal regeneration related protein |
PALLD | palladin, cytoskeletal associated protein |
PBX1 | pre-B-cell leukemia homeobox 1 |
PROM1 | prominin 1 |
PXDN | peroxidasin |
SOX4 | SRY (sex determining region Y)-box 4 |
SPRY2 | sprouty homolog 2 (Drosophila) |
STK38L | serine/threonine kinase 38 like |
SULF1 | sulfatase 1 |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
TFPI2 | tissue factor pathway inhibitor 2 |
TMSB15A | thymosin beta 15a |
TMSB15B | thymosin beta 15B |
TNPO1 | transportin 1 |
TRIB2 | tribbles pseudokinase 2 |
UGCG | UDP-glucose ceramide glucosyltransferase |
YPEL1 | yippee-like 1 (Drosophila) |
ZFAND5 | zinc finger, AN1-type domain 5 |
Symbol | Name |
---|---|
ABAT | 4-aminobutyrate aminotransferase |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ARG2 | arginase 2 |
CALB1 | calbindin 1, 28kDa |
CCDC86 | coiled-coil domain containing 86 |
CCND2 | cyclin D2 |
CCR7 | chemokine (C-C motif) receptor 7 |
CKB | creatine kinase, brain |
DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
DDIT4 | DNA-damage-inducible transcript 4 |
DHCR24 | 24-dehydrocholesterol reductase |
EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
EGR1 | early growth response 1 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FAM162A | family with sequence similarity 162, member A |
FASN | fatty acid synthase |
GATA2 | GATA binding protein 2 |
HSPE1 | heat shock 10kDa protein 1 |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
IGFBP3 | insulin-like growth factor binding protein 3 |
IL1R2 | interleukin 1 receptor, type II |
IL6ST | interleukin 6 signal transducer |
INSIG1 | insulin induced gene 1 |
ITGA6 | integrin, alpha 6 |
ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
MAL | mal, T-cell differentiation protein |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MSMB | microseminoprotein, beta- |
NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
NT5DC2 | 5'-nucleotidase domain containing 2 |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PAX8 | paired box 8 |
PGC | progastricsin (pepsinogen C) |
PRAME | preferentially expressed antigen in melanoma |
PSAT1 | phosphoserine aminotransferase 1 |
PSPH | phosphoserine phosphatase |
S100A2 | S100 calcium binding protein A2 |
SIAH2 | siah E3 ubiquitin protein ligase 2 |
SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
SPAG4 | sperm associated antigen 4 |
SUB1 | SUB1 homolog (S. cerevisiae) |
VDAC1 | voltage-dependent anion channel 1 |