Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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142 genes differentially expressed following the BRD-K52911425_GDC-0941_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ATP9A | ATPase, class II, type 9A |
BEX1 | brain expressed, X-linked 1 |
C14ORF132 | chromosome 14 open reading frame 132 |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
CLDN3 | claudin 3 |
CLEC2B | C-type lectin domain family 2, member B |
CREBL2 | cAMP responsive element binding protein-like 2 |
CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 |
CTSK | cathepsin K |
CXADR | coxsackie virus and adenovirus receptor |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DUSP6 | dual specificity phosphatase 6 |
ECM1 | extracellular matrix protein 1 |
EDN1 | endothelin 1 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
ENO2 | enolase 2 (gamma, neuronal) |
ETV1 | ets variant 1 |
EZR | ezrin |
FBXO11 | F-box protein 11 |
FCGBP | Fc fragment of IgG binding protein |
FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
FOXG1 | forkhead box G1 |
FXYD3 | FXYD domain containing ion transport regulator 3 |
HMGB3 | high mobility group box 3 |
HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
IFITM1 | interferon induced transmembrane protein 1 |
IFITM3 | interferon induced transmembrane protein 3 |
IRS2 | insulin receptor substrate 2 |
ITGB5 | integrin, beta 5 |
ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
JADE2 | jade family PHD finger 2 |
KDM5D | lysine (K)-specific demethylase 5D |
LAMA3 | laminin, alpha 3 |
MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
MAOA | monoamine oxidase A |
MLPH | melanophilin |
MMP11 | matrix metallopeptidase 11 |
MMP2 | matrix metallopeptidase 2 |
MPDZ | multiple PDZ domain protein |
MUC4 | mucin 4, cell surface associated |
MYO5C | myosin VC |
N4BP2L1 | NEDD4 binding protein 2-like 1 |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
NSG1 | neuron specific gene family member 1 |
NUP85 | nucleoporin 85kDa |
PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
PXDN | peroxidasin |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SATB1 | SATB homeobox 1 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
SLC35E2B | solute carrier family 35, member E2B |
SOX4 | SRY (sex determining region Y)-box 4 |
SPON1 | spondin 1, extracellular matrix protein |
SPRY2 | sprouty homolog 2 (Drosophila) |
TCEA2 | transcription elongation factor A (SII), 2 |
TMC5 | transmembrane channel-like 5 |
TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
TMSB15A | thymosin beta 15a |
TPP1 | tripeptidyl peptidase I |
VAT1 | vesicle amine transport 1 |
WDTC1 | WD and tetratricopeptide repeats 1 |
Symbol | Name |
---|---|
ADGRG1 | adhesion G protein-coupled receptor G1 |
AK4 | adenylate kinase 4 |
APOA2 | apolipoprotein A-II |
AQP3 | aquaporin 3 (Gill blood group) |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
BAG2 | BCL2-associated athanogene 2 |
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
CA12 | carbonic anhydrase XII |
CA2 | carbonic anhydrase II |
CALU | calumenin |
CCL2 | chemokine (C-C motif) ligand 2 |
CD36 | CD36 molecule (thrombospondin receptor) |
CKAP4 | cytoskeleton-associated protein 4 |
CLIC3 | chloride intracellular channel 3 |
COL9A3 | collagen, type IX, alpha 3 |
CTSC | cathepsin C |
CXCL12 | chemokine (C-X-C motif) ligand 12 |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DDIT4 | DNA-damage-inducible transcript 4 |
EGF | epidermal growth factor |
ELF5 | E74-like factor 5 (ets domain transcription factor) |
FAM162A | family with sequence similarity 162, member A |
FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
FGF13 | fibroblast growth factor 13 |
FKBP14 | FK506 binding protein 14, 22 kDa |
GGT1 | gamma-glutamyltransferase 1 |
GLIPR1 | GLI pathogenesis-related 1 |
GOLT1B | golgi transport 1B |
GPC3 | glypican 3 |
GRB14 | growth factor receptor-bound protein 14 |
HOMER1 | homer scaffolding protein 1 |
HOMER2 | homer scaffolding protein 2 |
IGFBP3 | insulin-like growth factor binding protein 3 |
INSIG1 | insulin induced gene 1 |
IRF4 | interferon regulatory factor 4 |
ITM2A | integral membrane protein 2A |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LDHB | lactate dehydrogenase B |
MINA | MYC induced nuclear antigen |
NOTCH2 | notch 2 |
NT5DC2 | 5'-nucleotidase domain containing 2 |
ODC1 | ornithine decarboxylase 1 |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PAX8 | paired box 8 |
PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
PDGFC | platelet derived growth factor C |
PEG10 | paternally expressed 10 |
PEX3 | peroxisomal biogenesis factor 3 |
PGM1 | phosphoglucomutase 1 |
PITX1 | paired-like homeodomain 1 |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
PNO1 | partner of NOB1 homolog (S. cerevisiae) |
PSAT1 | phosphoserine aminotransferase 1 |
PSPH | phosphoserine phosphatase |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SFRP1 | secreted frizzled-related protein 1 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SNAI2 | snail family zinc finger 2 |
SOX9 | SRY (sex determining region Y)-box 9 |
SRPRB | signal recognition particle receptor, B subunit |
TFRC | transferrin receptor |
TNC | tenascin C |
TPD52L1 | tumor protein D52-like 1 |
TUBB2A | tubulin, beta 2A class IIa |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
XIST | X inactive specific transcript (non-protein coding) |