| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
93 genes differentially expressed following the BRD-K53281329_SYK-inhibitor_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF4 | activating transcription factor 4 |
| ATM | ATM serine/threonine kinase |
| CD1E | CD1e molecule |
| CIRBP | cold inducible RNA binding protein |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM129A | family with sequence similarity 129, member A |
| FAM69A | family with sequence similarity 69, member A |
| G0S2 | G0/G1 switch 2 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 |
| IRS2 | insulin receptor substrate 2 |
| METRN | meteorin, glial cell differentiation regulator |
| MMP3 | matrix metallopeptidase 3 |
| MYBPC1 | myosin binding protein C, slow type |
| PHGDH | phosphoglycerate dehydrogenase |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLK2 | polo-like kinase 2 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSPH | phosphoserine phosphatase |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAI2 | snail family zinc finger 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| STC2 | stanniocalcin 2 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TFF3 | trefoil factor 3 (intestinal) |
| THBS4 | thrombospondin 4 |
| TNC | tenascin C |
| Symbol | Name |
|---|---|
| AEBP1 | AE binding protein 1 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| C1QB | complement component 1, q subcomponent, B chain |
| C7 | complement component 7 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD14 | CD14 molecule |
| CD163 | CD163 molecule |
| CD24 | CD24 molecule |
| CD47 | CD47 molecule |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CKB | creatine kinase, brain |
| CLIC3 | chloride intracellular channel 3 |
| CLTC | clathrin, heavy chain (Hc) |
| CLU | clusterin |
| COCH | cochlin |
| CYCS | cytochrome c, somatic |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FAM162A | family with sequence similarity 162, member A |
| HK1 | hexokinase 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| ITGB5 | integrin, beta 5 |
| KRT1 | keratin 1, type II |
| LXN | latexin |
| MATN2 | matrilin 2 |
| MGP | matrix Gla protein |
| MTUS1 | microtubule associated tumor suppressor 1 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like |
| NSG1 | neuron specific gene family member 1 |
| PCP4 | Purkinje cell protein 4 |
| PLBD1 | phospholipase B domain containing 1 |
| PON3 | paraoxonase 3 |
| RAI2 | retinoic acid induced 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SCEL | sciellin |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| STMN1 | stathmin 1 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
