BRD-K53308430_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K53308430_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP1 aquaporin 1 (Colton blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CD24 CD24 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC4 chloride intracellular channel 4
CPB1 carboxypeptidase B1 (tissue)
CTSZ cathepsin Z
DES desmin
DPYSL3 dihydropyrimidinase-like 3
FABP4 fatty acid binding protein 4, adipocyte
FBP1 fructose-1,6-bisphosphatase 1
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
GDF15 growth differentiation factor 15
IER3 immediate early response 3
IGFBP7 insulin-like growth factor binding protein 7
IL1RN interleukin 1 receptor antagonist
KRT18 keratin 18, type I
LDOC1 leucine zipper, down-regulated in cancer 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS2 lectin, galactoside-binding, soluble, 2
MMP7 matrix metallopeptidase 7
MYH11 myosin, heavy chain 11, smooth muscle
MYOF myoferlin
NEBL nebulette
NMU neuromedin U
NRGN neurogranin (protein kinase C substrate, RC3)
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PDGFC platelet derived growth factor C
PLBD1 phospholipase B domain containing 1
QPCT glutaminyl-peptide cyclotransferase
S100A4 S100 calcium binding protein A4
SDC4 syndecan 4
SMAD3 SMAD family member 3
SPP1 secreted phosphoprotein 1
SRGN serglycin
SYNM synemin, intermediate filament protein
TCTA T-cell leukemia translocation altered
TGM2 transglutaminase 2
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
MRPS2 mitochondrial ribosomal protein S2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PLTP phospholipid transfer protein
SLC39A14 solute carrier family 39 (zinc transporter), member 14
ZC3HAV1 zinc finger CCCH-type, antiviral 1