Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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97 genes differentially expressed following the BRD-K53414658_tivozanib_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADGRG2 | adhesion G protein-coupled receptor G2 |
AKAP12 | A kinase (PRKA) anchor protein 12 |
AMDHD2 | amidohydrolase domain containing 2 |
ASS1 | argininosuccinate synthase 1 |
BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CD24 | CD24 molecule |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CLGN | calmegin |
COBL | cordon-bleu WH2 repeat protein |
CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
DUSP4 | dual specificity phosphatase 4 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FABP7 | fatty acid binding protein 7, brain |
GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
IGLL1 | immunoglobulin lambda-like polypeptide 1 |
IRS2 | insulin receptor substrate 2 |
KIAA0368 | KIAA0368 |
KRT7 | keratin 7, type II |
LAMP1 | lysosomal-associated membrane protein 1 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
PRAME | preferentially expressed antigen in melanoma |
PSAT1 | phosphoserine aminotransferase 1 |
PTX3 | pentraxin 3, long |
S100P | S100 calcium binding protein P |
SCCPDH | saccharopine dehydrogenase (putative) |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
TM4SF1 | transmembrane 4 L six family member 1 |
TRIM2 | tripartite motif containing 2 |
UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
VCL | vinculin |
ZBTB16 | zinc finger and BTB domain containing 16 |
ZMIZ1 | zinc finger, MIZ-type containing 1 |
Symbol | Name |
---|---|
ABI1 | abl-interactor 1 |
AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
ATG3 | autophagy related 3 |
BICC1 | BicC family RNA binding protein 1 |
BLNK | B-cell linker |
C7 | complement component 7 |
CA12 | carbonic anhydrase XII |
CADM1 | cell adhesion molecule 1 |
CFI | complement factor I |
CLEC2B | C-type lectin domain family 2, member B |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
DACH1 | dachshund family transcription factor 1 |
DSP | desmoplakin |
EREG | epiregulin |
FAM69A | family with sequence similarity 69, member A |
FLRT3 | fibronectin leucine rich transmembrane protein 3 |
GTF2A2 | general transcription factor IIA, 2, 12kDa |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
HIST1H2BG | histone cluster 1, H2bg |
HIST1H4C | histone cluster 1, H4c |
HIST1H4J | histone cluster 1, H4j |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IFITM1 | interferon induced transmembrane protein 1 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IL2RB | interleukin 2 receptor, beta |
IPO13 | importin 13 |
KIF5B | kinesin family member 5B |
LEPR | leptin receptor |
LPAR6 | lysophosphatidic acid receptor 6 |
LYZ | lysozyme |
MB | myoglobin |
MEIS2 | Meis homeobox 2 |
MOXD1 | monooxygenase, DBH-like 1 |
PCP4 | Purkinje cell protein 4 |
PERP | PERP, TP53 apoptosis effector |
PLEK | pleckstrin |
PMM2 | phosphomannomutase 2 |
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
RAB25 | RAB25, member RAS oncogene family |
RGS1 | regulator of G-protein signaling 1 |
RTN1 | reticulon 1 |
S100A14 | S100 calcium binding protein A14 |
S100A8 | S100 calcium binding protein A8 |
SEPP1 | selenoprotein P, plasma, 1 |
SHB | Src homology 2 domain containing adaptor protein B |
SIRT3 | sirtuin 3 |
SOCS2 | suppressor of cytokine signaling 2 |
SRP54 | signal recognition particle 54kDa |
TBPL1 | TBP-like 1 |
TM9SF3 | transmembrane 9 superfamily member 3 |
TRAPPC6A | trafficking protein particle complex 6A |
TUSC3 | tumor suppressor candidate 3 |
YME1L1 | YME1-like 1 ATPase |
ZNF395 | zinc finger protein 395 |