BRD-K53417444_OTSSP167_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K53417444_OTSSP167_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCY9 adenylate cyclase 9
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AKAP8 A kinase (PRKA) anchor protein 8
ANKRD10 ankyrin repeat domain 10
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
CADM1 cell adhesion molecule 1
CD9 CD9 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CES1 carboxylesterase 1
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
FAM63A family with sequence similarity 63, member A
GADD45B growth arrest and DNA-damage-inducible, beta
GBP1 guanylate binding protein 1, interferon-inducible
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
HIST1H1C histone cluster 1, H1c
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-E major histocompatibility complex, class I, E
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
KIAA0125 KIAA0125
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MXRA5 matrix-remodelling associated 5
SCD5 stearoyl-CoA desaturase 5
SCPEP1 serine carboxypeptidase 1
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC12A8 solute carrier family 12, member 8
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SYBU syntabulin (syntaxin-interacting)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM30B transmembrane protein 30B
TWIST1 twist family bHLH transcription factor 1
ZBED2 zinc finger, BED-type containing 2
ZCCHC24 zinc finger, CCHC domain containing 24
ZMAT3 zinc finger, matrin-type 3
ZNF331 zinc finger protein 331
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMIGO2 adhesion molecule with Ig-like domain 2
ATF5 activating transcription factor 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL5 chemokine (C-X-C motif) ligand 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DYNLT1 dynein, light chain, Tctex-type 1
FABP7 fatty acid binding protein 7, brain
GLOD4 glyoxalase domain containing 4
GLRX glutaredoxin (thioltransferase)
GTF2A2 general transcription factor IIA, 2, 12kDa
HSPA1A heat shock 70kDa protein 1A
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
KIAA1033 KIAA1033
KRT19 keratin 19, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
NUP88 nucleoporin 88kDa
NUSAP1 nucleolar and spindle associated protein 1
PFKP phosphofructokinase, platelet
PLIN2 perilipin 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PSIP1 PC4 and SFRS1 interacting protein 1
PWP1 PWP1 homolog (S. cerevisiae)
S100A7 S100 calcium binding protein A7
S100P S100 calcium binding protein P
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SQSTM1 sequestosome 1
TBL1X transducin (beta)-like 1X-linked
TMEM47 transmembrane protein 47
TSPYL5 TSPY-like 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
XPO1 exportin 1
Funding