| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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118 genes differentially expressed following the BRD-K53461563_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ANXA3 | annexin A3 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARF1 | ADP-ribosylation factor 1 |
| ATF3 | activating transcription factor 3 |
| BMP2 | bone morphogenetic protein 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CADM1 | cell adhesion molecule 1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD9 | CD9 molecule |
| CELF2 | CUGBP, Elav-like family member 2 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRIP2 | cysteine-rich protein 2 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EGR1 | early growth response 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| EMP1 | epithelial membrane protein 1 |
| ERLIN2 | ER lipid raft associated 2 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IGHM | immunoglobulin heavy constant mu |
| KIAA0226L | KIAA0226-like |
| KLF6 | Kruppel-like factor 6 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MCL1 | myeloid cell leukemia 1 |
| MME | membrane metallo-endopeptidase |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PDLIM4 | PDZ and LIM domain 4 |
| POSTN | periostin, osteoblast specific factor |
| RGCC | regulator of cell cycle |
| RGS10 | regulator of G-protein signaling 10 |
| RPL10 | ribosomal protein L10 |
| SELENBP1 | selenium binding protein 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SLC38A1 | solute carrier family 38, member 1 |
| SMAD3 | SMAD family member 3 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| THBD | thrombomodulin |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| USP6NL | USP6 N-terminal like |
| VEGFA | vascular endothelial growth factor A |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AGR2 | anterior gradient 2 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| CALML4 | calmodulin-like 4 |
| CAST | calpastatin |
| CCNA1 | cyclin A1 |
| CCNF | cyclin F |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CTSZ | cathepsin Z |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DMD | dystrophin |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FGFR3 | fibroblast growth factor receptor 3 |
| FHL1 | four and a half LIM domains 1 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL17RB | interleukin 17 receptor B |
| ITM2A | integral membrane protein 2A |
| KAZN | kazrin, periplakin interacting protein |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LTF | lactotransferrin |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAP7 | microtubule-associated protein 7 |
| MSH6 | mutS homolog 6 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NMT1 | N-myristoyltransferase 1 |
| PDZK1 | PDZ domain containing 1 |
| PLK1 | polo-like kinase 1 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
| RAB26 | RAB26, member RAS oncogene family |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TNIK | TRAF2 and NCK interacting kinase |
| TPSAB1 | tryptase alpha/beta 1 |
